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Zinc in PDB 4kx9: Crystal Structure of Human Aminopeptidase A Complexed with Arginine

Enzymatic activity of Crystal Structure of Human Aminopeptidase A Complexed with Arginine

All present enzymatic activity of Crystal Structure of Human Aminopeptidase A Complexed with Arginine:
3.4.11.7;

Protein crystallography data

The structure of Crystal Structure of Human Aminopeptidase A Complexed with Arginine, PDB code: 4kx9 was solved by Y.Yang, C.Liu, Y.Y.Lin, F.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.59 / 2.25
Space group P 64 2 2
Cell size a, b, c (Å), α, β, γ (°) 142.272, 142.272, 237.233, 90.00, 90.00, 120.00
R / Rfree (%) 16.3 / 23.4

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Aminopeptidase A Complexed with Arginine (pdb code 4kx9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Aminopeptidase A Complexed with Arginine, PDB code: 4kx9:

Zinc binding site 1 out of 1 in 4kx9

Go back to Zinc Binding Sites List in 4kx9
Zinc binding site 1 out of 1 in the Crystal Structure of Human Aminopeptidase A Complexed with Arginine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Aminopeptidase A Complexed with Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:85.0
occ:1.00
OE1 A:GLU416 2.0 53.8 1.0
NE2 A:HIS397 2.2 56.1 1.0
NE2 A:HIS393 2.3 49.1 1.0
O A:HOH1586 2.8 73.9 1.0
CD A:GLU416 2.9 59.9 1.0
CD2 A:HIS397 3.1 54.9 1.0
CD2 A:HIS393 3.1 46.8 1.0
OE2 A:GLU416 3.2 70.5 1.0
CE1 A:HIS397 3.2 55.4 1.0
CE1 A:HIS393 3.4 49.1 1.0
C A:ARG1018 3.5 0.2 1.0
N A:ARG1018 3.5 0.4 1.0
OXT A:ARG1018 3.6 0.8 1.0
O A:ARG1018 3.6 98.9 1.0
OH A:TYR479 3.9 56.8 1.0
CE2 A:TYR479 4.0 43.9 1.0
CA A:ARG1018 4.0 96.2 1.0
CZ A:TYR479 4.3 49.9 1.0
ND1 A:HIS397 4.3 55.8 1.0
CG A:HIS397 4.3 56.0 1.0
CG A:GLU416 4.3 59.5 1.0
CG A:HIS393 4.4 44.1 1.0
OE1 A:GLU360 4.4 59.0 1.0
CB A:ALA419 4.4 53.4 1.0
ND1 A:HIS393 4.4 48.7 1.0
CA A:GLU416 4.6 53.3 1.0
CB A:GLU416 4.7 54.4 1.0
OE2 A:GLU360 4.7 56.5 1.0
CD A:GLU360 4.8 56.0 1.0
OE2 A:GLU394 4.8 54.1 1.0
O A:HOH1281 4.9 62.4 1.0

Reference:

Y.Yang, C.Liu, Y.L.Lin, F.Li. Structural Insights Into Central Hypertension Regulation By Human Aminopeptidase A. J.Biol.Chem. V. 288 25638 2013.
ISSN: ISSN 0021-9258
PubMed: 23888046
DOI: 10.1074/JBC.M113.494955
Page generated: Wed Dec 16 05:30:01 2020

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