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Atomistry » Zinc » PDB 4kjm-4kxc » 4kp6 » |
Zinc in PDB 4kp6: Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine DerivativeEnzymatic activity of Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative, PDB code: 4kp6
was solved by
R.Gewald,
C.Grunwald,
U.Egerland,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4kp6:
The structure of Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative
(pdb code 4kp6). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative, PDB code: 4kp6: Zinc binding site 1 out of 1 in 4kp6Go back to Zinc Binding Sites List in 4kp6
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Phosphodiesterase 4B (PDE4B) in Complex with A [1,3,5]Triazine Derivative
Mono view Stereo pair view
Reference:
R.Gewald,
C.Grunwald,
U.Egerland.
Discovery of Triazines As Potent, Selective and Orally Active PDE4 Inhibitors. Bioorg.Med.Chem.Lett. V. 23 4308 2013.
Page generated: Wed Dec 16 05:29:45 2020
ISSN: ISSN 0960-894X PubMed: 23806553 DOI: 10.1016/J.BMCL.2013.05.099 |
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