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Atomistry » Zinc » PDB 4ihm-4iuw » 4iue » |
Zinc in PDB 4iue: Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-OneEnzymatic activity of Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One
All present enzymatic activity of Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One:
2.4.2.30; Protein crystallography data
The structure of Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One, PDB code: 4iue
was solved by
A.E.Jansson,
E.A.Larsson,
P.L.Nordlund,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4iue:
The structure of Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One
(pdb code 4iue). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One, PDB code: 4iue: Zinc binding site 1 out of 1 in 4iueGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Tankyrase in Complex with 7-(2-Fluorophenyl)-4-Methyl-1,2- Dihydroquinolin-2-One
![]() Mono view ![]() Stereo pair view
Reference:
E.A.Larsson,
A.E.Jansson,
F.M.Ng,
S.W.Then,
R.Panicker,
B.Liu,
K.Sangthongpitag,
V.Pendharkar,
S.J.Tai,
J.Hill,
C.Dan,
S.Y.Ho,
W.W.Cheong,
A.Poulsen,
S.Blanchard,
G.R.Lin,
J.Alam,
T.H.Keller,
P.Nordlund.
Fragment-Based Ligand Design of Novel Potent Inhibitors of Tankyrases. J.Med.Chem. V. 56 4497 2013.
Page generated: Wed Dec 16 05:24:37 2020
ISSN: ISSN 0022-2623 PubMed: 23672613 DOI: 10.1021/JM400211F |
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