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Zinc in PDB 4h49: Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Enzymatic activity of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.:
3.4.24.65;
3.4.24.65;
Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor., PDB code: 4h49
was solved by
C.Antoni,
E.A.Stura,
L.Vera,
E.Nuti,
L.Carafa,
E.Cassar-Lajeunesse,
V.Dive,
A.Rossello,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.26 / 2.16 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 47.440, 106.490, 65.880, 90.00, 94.96, 90.00 |
| R / Rfree (%) | 16.7 / 24.1 |
Other elements in 4h49:
The structure of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. also contains other interesting chemical elements:
| Calcium | (Ca) | 12 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
(pdb code 4h49). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor., PDB code: 4h49:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Zinc where determined in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor., PDB code: 4h49:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Zinc binding site 1 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 1 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 2 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 2 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 3 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 3 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 4 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 4 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 5 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 5 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 6 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 6 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 7 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 7 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Zinc binding site 8 out of 8 in 4h49
Go back to
Zinc Binding Sites List in 4h49
Zinc binding site 8 out
of 8 in the Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Crystal Structure of the Catalytic Domain of Mmp-12 in Complex with A Twin Inhibitor. within 5.0Å range:
|
Reference:
C.Antoni,
L.Vera,
L.Devel,
M.P.Catalani,
B.Czarny,
E.Cassar-Lajeunesse,
E.Nuti,
A.Rossello,
V.Dive,
E.A.Stura.
Crystallization of Bi-Functional Ligand Protein Complexes. J.Struct.Biol. V. 182 246 2013.
ISSN: ISSN 1047-8477
PubMed: 23567804
DOI: 10.1016/J.JSB.2013.03.015
Page generated: Sat Oct 26 23:53:37 2024
ISSN: ISSN 1047-8477
PubMed: 23567804
DOI: 10.1016/J.JSB.2013.03.015
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