Zinc in PDB 4gb0: Crystal Structure of the Ring Domain of RNF168

The structure of Crystal Structure of the Ring Domain of RNF168, PDB code: 4gb0 was solved by X.Q.Zhang, C.L.Wang, J.Y.Zang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.47 / 2.60
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	50.160, 50.160, 113.930, 90.00, 90.00, 90.00
R / Rfree (%)	22.3 / 27.6

The binding sites of Zinc atom in the Crystal Structure of the Ring Domain of RNF168 (pdb code 4gb0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Ring Domain of RNF168, PDB code: 4gb0:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Ring Domain of RNF168


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Ring Domain of RNF168 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:48.3 occ:1.00 ND1 A:HIS33 2.2 53.3 1.0 SG A:CYS31 2.2 44.9 1.0 SG A:CYS51 2.3 50.3 1.0 SG A:CYS54 2.4 50.4 1.0 CB A:CYS51 3.0 51.3 1.0 CE1 A:HIS33 3.1 52.6 1.0 CB A:CYS31 3.1 47.1 1.0 CG A:HIS33 3.1 50.3 1.0 CB A:CYS54 3.4 48.8 1.0 CB A:HIS33 3.5 47.5 1.0 N A:CYS54 3.9 50.3 1.0 CA A:CYS54 4.2 50.4 1.0 NE2 A:HIS33 4.2 53.6 1.0 CD2 A:HIS33 4.2 50.6 1.0 CB A:PHE53 4.4 50.1 1.0 N A:HIS33 4.5 49.0 1.0 CA A:CYS31 4.5 47.1 1.0 CA A:CYS51 4.5 51.8 1.0 CB A:ARG56 4.5 50.5 1.0 CA A:HIS33 4.6 47.5 1.0 C A:PHE53 4.7 50.5 1.0 C A:CYS31 4.8 48.9 1.0 C A:CYS54 4.8 50.3 1.0 CD1 A:LEU29 4.9 43.7 1.0 N A:PHE53 4.9 50.3 1.0 CA A:PHE53 4.9 50.3 1.0 O A:CYS31 4.9 49.1 1.0 N A:ARG55 4.9 50.4 1.0 CD2 A:PHE53 5.0 50.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Ring Domain of RNF168


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Ring Domain of RNF168 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:52.1 occ:1.00 SG A:CYS36 2.3 44.5 1.0 SG A:CYS39 2.4 63.3 1.0 SG A:CYS16 2.4 53.7 1.0 SG A:CYS19 2.5 59.8 1.0 CB A:CYS16 3.0 53.3 1.0 CB A:CYS39 3.2 60.1 1.0 CB A:CYS36 3.3 47.5 1.0 CB A:CYS19 3.6 57.5 1.0 N A:CYS36 3.8 47.0 1.0 N A:CYS19 4.1 57.5 1.0 CA A:CYS36 4.1 48.0 1.0 N A:CYS39 4.2 59.2 1.0 CA A:CYS39 4.3 60.2 1.0 NH1 A:ARG91 4.4 57.8 1.0 CA A:CYS19 4.4 57.9 1.0 CA A:CYS16 4.5 53.5 1.0 O A:CYS36 4.5 49.7 1.0 C A:CYS36 4.7 49.6 1.0 NH2 A:ARG91 4.8 62.1 1.0 CB A:ILE18 4.8 55.7 1.0

X.Q.Zhang, J.Chen, M.Wu, H.Wu, A.W.Arokiaraj, C.L.Wang, W.Zhang, Y.Tao, M.S.Huen, J.Y.Zang. Structural Basis For Role of Ring Finger Protein RNF168 Ring Domain Cell Cycle V. 12 312 2013.
ISSN: ISSN 1538-4101
PubMed: 23255131
DOI: 10.4161/CC.23104