Zinc in PDB 4g9z: Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression

The structure of Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression, PDB code: 4g9z was solved by X.Jiang, Q.Huang, W.Wang, H.Dong, H.Ly, Y.Liang, C.Dong, Scottish Structuralproteomics Facility (Sspf), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.33 / 2.03
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	46.744, 46.744, 217.315, 90.00, 90.00, 90.00
R / Rfree (%)	20.3 / 24

The binding sites of Zinc atom in the Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression (pdb code 4g9z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression, PDB code: 4g9z:

Zinc binding site 1 out of 1 in the Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Lassa Nucleoprotein with Dsrna Reveals Novel Mechanism For Immune Suppression within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:13.3 occ:1.00 OE2 A:GLU399 2.1 12.4 1.0 NE2 A:HIS509 2.1 15.8 1.0 SG A:CYS529 2.2 12.0 1.0 SG A:CYS506 2.2 14.6 1.0 CD2 A:HIS509 3.0 15.9 1.0 CD A:GLU399 3.0 11.7 1.0 CB A:CYS529 3.2 12.2 1.0 CE1 A:HIS509 3.2 15.3 1.0 OE1 A:GLU399 3.3 11.7 1.0 CB A:CYS506 3.3 15.0 1.0 CA A:CYS529 3.8 12.4 1.0 NE2 A:HIS412 3.8 13.4 1.0 CE1 A:HIS412 4.1 13.5 1.0 CG A:HIS509 4.2 17.0 1.0 N A:ALA530 4.2 12.1 1.0 ND1 A:HIS509 4.3 16.1 1.0 CZ A:PHE414 4.4 18.6 1.0 C A:CYS529 4.4 12.1 1.0 CG A:GLU399 4.4 12.2 1.0 CE1 A:PHE414 4.6 19.8 1.0 CA A:CYS506 4.7 16.0 1.0 N A:LEU531 4.8 9.9 1.0 CB A:MET508 4.8 22.6 1.0

X.Jiang, Q.Huang, W.Wang, H.Dong, H.Ly, Y.Liang, C.Dong. Structures of Arenaviral Nucleoproteins with Triphosphate Dsrna Reveal A Unique Mechanism of Immune Suppression. J.Biol.Chem. V. 288 16949 2013.
ISSN: ISSN 0021-9258
PubMed: 23615902
DOI: 10.1074/JBC.M112.420521