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Zinc in PDB 4g4n: Mutm Containing M77A Mutation Bound to Undamaged Dna

Enzymatic activity of Mutm Containing M77A Mutation Bound to Undamaged Dna

All present enzymatic activity of Mutm Containing M77A Mutation Bound to Undamaged Dna:
3.2.2.23;

Protein crystallography data

The structure of Mutm Containing M77A Mutation Bound to Undamaged Dna, PDB code: 4g4n was solved by R.J.Sung, M.Zhang, Y.Qi, G.L.Verdine, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.69 / 1.85
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 45.188, 93.541, 104.650, 90.00, 90.00, 90.00
R / Rfree (%) 16.9 / 19.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Mutm Containing M77A Mutation Bound to Undamaged Dna (pdb code 4g4n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Mutm Containing M77A Mutation Bound to Undamaged Dna, PDB code: 4g4n:

Zinc binding site 1 out of 1 in 4g4n

Go back to Zinc Binding Sites List in 4g4n
Zinc binding site 1 out of 1 in the Mutm Containing M77A Mutation Bound to Undamaged Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mutm Containing M77A Mutation Bound to Undamaged Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn300

b:17.9
occ:1.00
SG A:CYS269 2.3 16.7 1.0
SG A:CYS272 2.3 23.7 1.0
SG A:CYS252 2.3 17.2 1.0
SG A:CYS249 2.3 16.1 1.0
CB A:CYS249 3.1 16.2 1.0
CB A:CYS269 3.3 11.6 1.0
CB A:CYS272 3.4 19.1 1.0
CB A:CYS252 3.4 15.5 1.0
N A:CYS252 3.8 17.6 1.0
N A:CYS272 3.9 17.7 1.0
CE1 A:PHE182 4.1 17.4 1.0
CA A:CYS252 4.2 14.5 1.0
CA A:CYS272 4.2 16.8 1.0
O A:HOH555 4.5 32.2 1.0
CB A:ARG251 4.6 19.1 1.0
CA A:CYS249 4.6 18.8 1.0
CZ A:PHE182 4.6 17.5 1.0
CB A:ARG271 4.6 19.6 1.0
CB A:THR254 4.7 20.5 1.0
C A:ARG251 4.7 17.4 1.0
CA A:CYS269 4.7 14.4 1.0
C A:CYS252 4.8 18.4 1.0
N A:GLY253 4.8 18.4 1.0
C A:ARG271 4.9 19.0 1.0
OG1 A:THR254 5.0 19.5 1.0
N A:THR254 5.0 17.7 1.0
N A:ARG251 5.0 18.3 1.0

Reference:

R.J.Sung, M.Zhang, Y.Qi, G.L.Verdine. Structural and Biochemical Analysis of Dna Helix Invasion By the Bacterial 8-Oxoguanine Dna Glycosylase Mutm. J.Biol.Chem. V. 288 10012 2013.
ISSN: ISSN 0021-9258
PubMed: 23404556
DOI: 10.1074/JBC.M112.415612
Page generated: Wed Dec 16 05:18:59 2020

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