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Atomistry » Zinc » PDB 4f6n-4fkb » 4fcd | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4f6n-4fkb » 4fcd » |
Zinc in PDB 4fcd: Potent and Selective Phosphodiesterase 10A InhibitorsEnzymatic activity of Potent and Selective Phosphodiesterase 10A Inhibitors
All present enzymatic activity of Potent and Selective Phosphodiesterase 10A Inhibitors:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Potent and Selective Phosphodiesterase 10A Inhibitors, PDB code: 4fcd
was solved by
K.D.Parris,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4fcd:
The structure of Potent and Selective Phosphodiesterase 10A Inhibitors also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Potent and Selective Phosphodiesterase 10A Inhibitors
(pdb code 4fcd). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Potent and Selective Phosphodiesterase 10A Inhibitors, PDB code: 4fcd: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4fcdGo back to Zinc Binding Sites List in 4fcd
Zinc binding site 1 out
of 2 in the Potent and Selective Phosphodiesterase 10A Inhibitors
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4fcdGo back to Zinc Binding Sites List in 4fcd
Zinc binding site 2 out
of 2 in the Potent and Selective Phosphodiesterase 10A Inhibitors
Mono view Stereo pair view
Reference:
M.S.Malamas,
H.Stange,
R.Schindler,
H.J.Lankau,
C.Grunwald,
B.Langen,
U.Egerland,
T.Hage,
Y.Ni,
J.Erdei,
K.Y.Fan,
K.Parris,
K.L.Marquis,
S.Grauer,
J.Brennan,
R.Navarra,
R.Graf,
B.L.Harrison,
A.Robichaud,
T.Kronbach,
M.N.Pangalos,
N.J.Brandon,
N.Hoefgen.
Novel Triazines As Potent and Selective Phosphodiesterase 10A Inhibitors. Bioorg.Med.Chem.Lett. V. 22 5876 2012.
Page generated: Wed Dec 16 05:17:19 2020
ISSN: ISSN 0960-894X PubMed: 22902656 DOI: 10.1016/J.BMCL.2012.07.076 |
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