Zinc in PDB 4f3g: Kainate Bound to the Ligand Binding Domain of GLUA3I

The structure of Kainate Bound to the Ligand Binding Domain of GLUA3I, PDB code: 4f3g was solved by A.H.Ahmed, R.E.Oswald, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.15 / 2.06
Space group	P 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	47.657, 49.028, 136.639, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 24.5

The binding sites of Zinc atom in the Kainate Bound to the Ligand Binding Domain of GLUA3I (pdb code 4f3g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Kainate Bound to the Ligand Binding Domain of GLUA3I, PDB code: 4f3g:

Zinc binding site 1 out of 1 in the Kainate Bound to the Ligand Binding Domain of GLUA3I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Kainate Bound to the Ligand Binding Domain of GLUA3I within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:36.5 occ:1.00 NE2 A:HIS23 2.5 32.0 1.0 CE1 A:HIS23 3.4 31.2 1.0 CD2 A:HIS23 3.5 31.2 1.0 OE2 A:GLU24 3.7 36.5 1.0 ND1 A:HIS23 4.5 29.2 1.0 CG A:HIS23 4.6 30.6 1.0 CD A:GLU24 4.7 35.8 1.0 CD2 A:TYR19 4.8 33.7 1.0 CG A:GLU24 4.9 36.5 1.0 O A:HOH529 4.9 46.6 1.0

S.M.Holley, A.H.Ahmed, J.Srinivasan, S.E.Murthy, G.A.Weiland, R.E.Oswald, L.M.Nowak. The Loss of An Electrostatic Contact Unique to Ampa Receptor Ligand Binding Domain 2 Slows Channel Activation. Biochemistry V. 51 4015 2012.
ISSN: ISSN 0006-2960
PubMed: 22512472
DOI: 10.1021/BI3001837