|
Atomistry » Zinc » PDB 4eez-4eyf » 4eux | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4eez-4eyf » 4eux » |
Zinc in PDB 4eux: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine, PDB code: 4eux
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4eux:
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine
(pdb code 4eux). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine, PDB code: 4eux: Zinc binding site 1 out of 1 in 4euxGo back to Zinc Binding Sites List in 4eux
Zinc binding site 1 out
of 1 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(5-(((3R,4R)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Pentyl)-4-Methylpyridin-2-Amine
Mono view Stereo pair view
Reference:
H.Huang,
H.Ji,
H.Li,
Q.Jing,
K.J.Labby,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Selective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights From Molecular Dynamics Simulations. J.Am.Chem.Soc. V. 134 11559 2012.
Page generated: Wed Dec 16 05:16:19 2020
ISSN: ISSN 0002-7863 PubMed: 22731813 DOI: 10.1021/JA302269R |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |