Zinc in PDB 4e7j: Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution

All present enzymatic activity of Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution:
2.7.7.49; 2.7.7.7; 3.1.26.4;

The structure of Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution, PDB code: 4e7j was solved by G.N.Maertens, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.98 / 3.15
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	159.339, 159.339, 127.197, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 26.4

The binding sites of Zinc atom in the Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution (pdb code 4e7j). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution, PDB code: 4e7j:

Zinc binding site 1 out of 1 in the Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pfv Integrase Target Capture Complex, Apo Form (Tcc-Apo), at 3.15 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:60.6 occ:1.00 NE2 A:HIS62 2.0 61.0 1.0 ND1 A:HIS66 2.0 72.2 1.0 SG A:CYS99 2.3 76.7 1.0 SG A:CYS96 2.4 71.5 1.0 CE1 A:HIS62 2.9 63.8 1.0 CG A:HIS66 3.0 76.7 1.0 CE1 A:HIS66 3.1 63.8 1.0 CD2 A:HIS62 3.1 64.2 1.0 CB A:HIS66 3.2 75.6 1.0 CB A:CYS99 3.2 53.1 1.0 CB A:CYS96 3.6 61.0 1.0 CA A:HIS66 3.8 65.9 1.0 N A:CYS99 3.8 68.4 1.0 CA A:CYS99 4.1 51.5 1.0 ND1 A:HIS62 4.1 55.8 1.0 CD2 A:HIS66 4.1 68.1 1.0 NE2 A:HIS66 4.2 69.4 1.0 CG A:HIS62 4.2 56.9 1.0 O A:HIS66 4.4 69.3 1.0 C A:HIS66 4.4 61.6 1.0 C A:GLN98 4.9 71.6 1.0 CB A:GLN98 4.9 63.9 1.0 CA A:CYS96 5.0 74.0 1.0

S.Hare, G.N.Maertens, P.Cherepanov. 3'-Processing and Strand Transfer Catalysed By Retroviral Integrase in Crystallo. Embo J. V. 468 326 2012.
ISSN: ISSN 0261-4189
PubMed: 22580823
DOI: 10.1038/EMBOJ.2012.118