Zinc in PDB 4ct0: Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2

The structure of Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2, PDB code: 4ct0 was solved by I.Schmalen, J.Rajan Prabu, C.Benda, E.Wolf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.496 / 2.45
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	99.736, 99.736, 178.632, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 23.31

The structure of Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2 (pdb code 4ct0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2, PDB code: 4ct0:

Zinc binding site 1 out of 1 in the Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mouse CRYPTOCHROME1 in Complex with PERIOD2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1497 b:77.7 occ:1.00 NE2 A:HIS473 2.0 96.3 1.0 SG A:CYS414 2.2 79.1 1.0 SG B:CYS1210 2.3 0.8 1.0 SG B:CYS1213 2.6 0.9 1.0 CD2 A:HIS473 2.8 79.8 1.0 CB B:CYS1210 3.1 76.4 1.0 CE1 A:HIS473 3.1 73.0 1.0 CB A:CYS414 3.4 88.7 1.0 CB B:CYS1213 3.8 0.6 1.0 CG A:HIS473 4.0 96.8 1.0 CA A:CYS414 4.1 70.3 1.0 ND1 A:HIS473 4.1 72.8 1.0 N B:CYS1213 4.3 0.5 1.0 CD A:PRO415 4.3 75.6 1.0 CA B:CYS1210 4.5 84.9 1.0 CA B:CYS1213 4.6 0.1 1.0 CD2 B:TYR1212 4.7 0.4 1.0 CB B:TYR1212 4.9 97.6 1.0 C A:CYS414 4.9 74.8 1.0 N A:PRO415 4.9 76.8 1.0 C B:CYS1210 5.0 90.6 1.0 O B:CYS1210 5.0 98.9 1.0

I.Schmalen, S.Reischl, T.Wallach, R.Klemz, A.Grudziecki, J.R.Prabu, C.Benda, A.Kramer, E.Wolf. Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated By Zinc Binding and Disulfide Bond Formation. Cell(Cambridge,Mass.) V. 157 1203 2014.
ISSN: ISSN 0092-8674
PubMed: 24855952
DOI: 10.1016/J.CELL.2014.03.057