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Atomistry » Zinc » PDB 4c6p-4ci3 » 4cdt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4c6p-4ci3 » 4cdt » |
Zinc in PDB 4cdt: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine, PDB code: 4cdt
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4cdt:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine
(pdb code 4cdt). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine, PDB code: 4cdt: Zinc binding site 1 out of 1 in 4cdtGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin- 2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
M.A.Cinelli,
H.Li,
G.Chreifi,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Simplified 2-Aminoquinoline-Based Scaffold For Potent and Selective Neuronal Nitric Oxide Synthase Inhibition. J.Med.Chem. V. 57 1513 2014.
Page generated: Sat Oct 26 20:45:33 2024
ISSN: ISSN 0022-2623 PubMed: 24472039 DOI: 10.1021/JM401838X |
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