Zinc in PDB 4ca2: Engineering the Hydrophobic Pocket of Carbonic Anhydrase II

All present enzymatic activity of Engineering the Hydrophobic Pocket of Carbonic Anhydrase II:
4.2.1.1;

The structure of Engineering the Hydrophobic Pocket of Carbonic Anhydrase II, PDB code: 4ca2 was solved by R.S.Alexander, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.700, 41.700, 73.000, 90.00, 104.60, 90.00
R / Rfree (%)	n/a / n/a

The structure of Engineering the Hydrophobic Pocket of Carbonic Anhydrase II also contains other interesting chemical elements:

Mercury

(Hg)

1 atom

The binding sites of Zinc atom in the Engineering the Hydrophobic Pocket of Carbonic Anhydrase II (pdb code 4ca2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Engineering the Hydrophobic Pocket of Carbonic Anhydrase II, PDB code: 4ca2:

Zinc binding site 1 out of 1 in the Engineering the Hydrophobic Pocket of Carbonic Anhydrase II


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Engineering the Hydrophobic Pocket of Carbonic Anhydrase II within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn262 b:10.8 occ:1.00 NE2 A:HIS96 2.1 0.5 1.0 ND1 A:HIS119 2.2 5.6 1.0 NE2 A:HIS94 2.3 2.8 1.0 O A:HOH365 2.4 6.5 1.0 CE1 A:HIS96 3.0 0.5 1.0 CE1 A:HIS119 3.1 6.2 1.0 CD2 A:HIS94 3.1 2.4 1.0 CD2 A:HIS96 3.2 0.6 1.0 CG A:HIS119 3.3 5.5 1.0 CE1 A:HIS94 3.5 2.5 1.0 OG1 A:THR199 3.6 4.5 1.0 O A:HOH354 3.8 17.1 1.0 CB A:HIS119 3.9 4.9 1.0 OE1 A:GLU106 3.9 7.5 1.0 ND1 A:HIS96 4.1 0.8 1.0 O A:HOH358 4.2 43.7 1.0 CG A:HIS96 4.2 0.9 1.0 NE2 A:HIS119 4.3 6.2 1.0 CG A:HIS94 4.3 2.6 1.0 CD2 A:HIS119 4.4 5.9 1.0 ND1 A:HIS94 4.5 2.9 1.0 CD A:GLU106 4.8 7.0 1.0 CB A:THR199 5.0 4.4 1.0

R.S.Alexander, S.K.Nair, D.W.Christianson. Engineering the Hydrophobic Pocket of Carbonic Anhydrase II. Biochemistry V. 30 11064 1991.
ISSN: ISSN 0006-2960
PubMed: 1932029
DOI: 10.1021/BI00110A008