Zinc in PDB 4c25: L-Fuculose 1-Phosphate Aldolase

All present enzymatic activity of L-Fuculose 1-Phosphate Aldolase:
4.1.2.17;

The structure of L-Fuculose 1-Phosphate Aldolase, PDB code: 4c25 was solved by M.A.Higgins, M.D.L.Suits, C.Marsters, A.B.Boraston, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	80.25 / 2.03
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	113.490, 113.490, 41.300, 90.00, 90.00, 90.00
R / Rfree (%)	22.312 / 27.799

The structure of L-Fuculose 1-Phosphate Aldolase also contains other interesting chemical elements:

Nickel

(Ni)

1 atom

The binding sites of Zinc atom in the L-Fuculose 1-Phosphate Aldolase (pdb code 4c25). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the L-Fuculose 1-Phosphate Aldolase, PDB code: 4c25:

Zinc binding site 1 out of 1 in the L-Fuculose 1-Phosphate Aldolase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of L-Fuculose 1-Phosphate Aldolase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:33.9 occ:1.00 NE2 A:HIS93 2.0 30.4 1.0 NE2 A:HIS155 2.0 16.7 1.0 NE2 A:HIS95 2.1 37.3 1.0 O3 A:13P303 2.2 33.2 0.4 O2 A:13P303 2.2 37.3 0.4 O A:GLY25 2.7 37.8 0.6 CD2 A:HIS93 2.9 29.4 1.0 CE1 A:HIS155 3.0 21.5 1.0 C2 A:13P303 3.0 38.3 0.4 CE1 A:HIS95 3.0 39.7 1.0 CD2 A:HIS155 3.0 19.5 1.0 CE1 A:HIS93 3.0 33.7 1.0 C3 A:13P303 3.2 35.1 0.4 CD2 A:HIS95 3.2 37.6 1.0 C A:GLY25 3.5 41.1 0.6 CA A:GLY25 3.9 43.4 0.6 CG A:HIS93 4.1 31.3 1.0 ND1 A:HIS93 4.1 32.7 1.0 ND1 A:HIS155 4.1 21.1 1.0 ND1 A:HIS95 4.2 37.1 1.0 CG A:HIS155 4.2 20.3 1.0 CG A:HIS95 4.3 37.6 1.0 N A:GLY26 4.3 47.3 0.4 OE2 A:GLU74 4.3 46.6 1.0 C1 A:13P303 4.5 40.6 0.4 O A:HOH2100 4.5 40.9 1.0 N A:GLY26 4.6 40.3 0.6 CG A:GLU74 4.8 39.2 1.0 CA A:GLY26 5.0 41.2 0.4

M.A.Higgins, M.D.Suits, C.Marsters, A.B.Boraston. Structural and Functional Analysis of Fucose-Processing Enzymes From Streptococcus Pneumoniae. J.Mol.Biol. V. 426 1469 2014.
ISSN: ISSN 0022-2836
PubMed: 24333485
DOI: 10.1016/J.JMB.2013.12.006