Zinc in PDB 4bmb: Crystal Structure of the N Terminal Domain of Human Galectin 8

The structure of Crystal Structure of the N Terminal Domain of Human Galectin 8, PDB code: 4bmb was solved by E.Buzamet, F.M.Ruiz, M.Menendez, A.Romero, H.J.Gabius, D.Solis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.932 / 1.35
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	49.516, 49.516, 160.476, 90.00, 90.00, 90.00
R / Rfree (%)	15.86 / 17.73

The structure of Crystal Structure of the N Terminal Domain of Human Galectin 8 also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the N Terminal Domain of Human Galectin 8 (pdb code 4bmb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the N Terminal Domain of Human Galectin 8, PDB code: 4bmb:

Zinc binding site 1 out of 1 in the Crystal Structure of the N Terminal Domain of Human Galectin 8


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the N Terminal Domain of Human Galectin 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1154 b:18.3 occ:0.53 O A:HOH2099 1.7 17.0 1.0 ND1 A:HIS38 2.1 18.7 0.5 NE2 A:HIS147 2.2 21.2 1.0 O A:HOH2100 2.3 20.2 1.0 CE1 A:HIS38 2.9 24.4 0.7 CE1 A:HIS147 3.1 32.6 1.0 CD2 A:HIS147 3.2 24.1 1.0 CG A:HIS38 3.3 25.6 1.0 CB A:HIS38 3.7 28.0 1.0 CB A:SER102 3.9 23.1 1.0 NE2 A:HIS38 4.1 27.3 0.7 ND1 A:HIS147 4.2 28.5 1.0 CG A:HIS147 4.3 19.4 1.0 CD2 A:HIS38 4.3 24.1 0.6 O A:HOH2095 4.4 26.6 1.0 O A:GLY37 4.4 17.9 1.0 C A:GLY37 4.7 17.3 1.0 CA A:SER102 4.7 16.6 1.0 CA A:HIS38 4.7 17.2 1.0 OG A:SER102 4.9 30.7 1.0 N A:HIS38 4.9 17.1 1.0

F.M.Ruiz, B.A.Scholz, E.Buzamet, J.Kopitz, S.Andre, M.Menendez, A.Romero, D.Solis, H.J.Gabius. Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells. Febs J. V. 281 1446 2014.
ISSN: ISSN 1742-464X
PubMed: 24418318
DOI: 10.1111/FEBS.12716