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Atomistry » Zinc » PDB 4ad9-4arf » 4agp » |
Zinc in PDB 4agp: Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176Protein crystallography data
The structure of Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176, PDB code: 4agp
was solved by
A.C.Joerger,
R.Wilcken,
A.R.Fersht,
F.M.Boeckler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4agp:
The structure of Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176
(pdb code 4agp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176, PDB code: 4agp: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4agpGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 4agpGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Structure of the P53 Core Domain Mutant Y220C Bound to the Stabilizing Small Molecule PHIKAN5176
![]() Mono view ![]() Stereo pair view
Reference:
R.Wilcken,
X.Liu,
M.O.Zimmermann,
T.J.Rutherford,
A.R.Fersht,
A.C.Joerger,
F.M.Boeckler.
Halogen-Enriched Fragment Libraries As Leads For Drug Rescue of Mutant P53. J.Am.Chem.Soc. V. 134 6810 2012.
Page generated: Sat Oct 26 19:12:59 2024
ISSN: ISSN 0002-7863 PubMed: 22439615 DOI: 10.1021/JA301056A |
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