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Atomistry » Zinc » PDB 3zqz-4a3e » 4a1x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3zqz-4a3e » 4a1x » |
Zinc in PDB 4a1x: Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data)Enzymatic activity of Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data)
All present enzymatic activity of Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data):
3.4.21.98; 3.6.1.15; 3.6.4.13; Protein crystallography data
The structure of Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data), PDB code: 4a1x
was solved by
S.Schmelz,
J.Kuegler,
J.Collins,
D.Heinz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4a1x:
The structure of Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data) also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data)
(pdb code 4a1x). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data), PDB code: 4a1x: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4a1xGo back to Zinc Binding Sites List in 4a1x
Zinc binding site 1 out
of 2 in the Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data)
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4a1xGo back to Zinc Binding Sites List in 4a1x
Zinc binding site 2 out
of 2 in the Co-Complex Structure of NS3-4A Protease with the Inhibitory Peptide CP5-46-A (Synchrotron Data)
Mono view Stereo pair view
Reference:
J.Kugler,
S.Schmelz,
J.Gentzsch,
S.Haid,
E.Pollmann,
J.Van Den Heuvel,
R.Franke,
T.Pietschmann,
D.W.Heinz,
J.Collins.
High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem. V. 287 39224 2012.
Page generated: Sat Oct 26 18:48:27 2024
ISSN: ISSN 0021-9258 PubMed: 22965230 DOI: 10.1074/JBC.M112.393843 |
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