Zinc in PDB 3wv6: Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9

The structure of Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9, PDB code: 3wv6 was solved by H.Yoshida, S.Kamitori, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.85 / 1.95
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	58.340, 94.870, 64.810, 90.00, 113.87, 90.00
R / Rfree (%)	18.8 / 22.2

The binding sites of Zinc atom in the Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9 (pdb code 3wv6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9, PDB code: 3wv6:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:15.9 occ:1.00 NE2 A:HIS320 2.0 15.0 1.0 OD2 A:ASP100 2.0 15.6 1.0 NE2 A:HIS188 2.1 19.8 1.0 SG A:CYS102 2.2 18.8 1.0 CG A:ASP100 2.8 15.0 1.0 OD1 A:ASP100 2.9 14.4 1.0 CD2 A:HIS188 2.9 17.7 1.0 CD2 A:HIS320 2.9 13.8 1.0 CE1 A:HIS320 3.0 14.2 1.0 CE1 A:HIS188 3.1 20.1 1.0 O A:HOH501 3.5 11.8 1.0 CB A:CYS102 3.5 14.7 1.0 CG A:HIS188 4.1 19.4 1.0 CG A:HIS320 4.1 14.2 1.0 ND1 A:HIS188 4.1 18.5 1.0 ND1 A:HIS320 4.1 11.2 1.0 CB A:ASP100 4.2 14.3 1.0 O A:HOH722 4.3 41.2 1.0 CG2 A:THR32 4.4 17.2 1.0 OG1 A:THR32 4.5 18.2 1.0 CG2 A:THR319 4.5 17.1 1.0 N A:CYS102 4.6 12.5 1.0 CA A:CYS102 4.7 14.0 1.0 OE1 A:GLN30 4.7 25.7 1.0 C A:ASP100 4.9 14.2 1.0 O A:PRO187 5.0 20.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:16.6 occ:1.00 OD2 B:ASP100 2.0 15.2 1.0 NE2 B:HIS320 2.0 15.1 1.0 NE2 B:HIS188 2.1 20.5 1.0 SG B:CYS102 2.2 19.2 1.0 CG B:ASP100 2.8 15.6 1.0 CD2 B:HIS188 2.9 17.7 1.0 OD1 B:ASP100 2.9 15.6 1.0 CD2 B:HIS320 3.0 15.8 1.0 CE1 B:HIS320 3.0 15.1 1.0 CE1 B:HIS188 3.2 19.2 1.0 O B:HOH503 3.5 13.7 1.0 CB B:CYS102 3.5 15.0 1.0 CG B:HIS188 4.1 18.2 1.0 ND1 B:HIS320 4.1 14.9 1.0 CG B:HIS320 4.1 16.6 1.0 ND1 B:HIS188 4.2 18.7 1.0 CB B:ASP100 4.2 14.5 1.0 CG2 B:THR32 4.4 16.9 1.0 O B:HOH662 4.4 27.7 1.0 CG2 B:THR319 4.4 20.8 1.0 OG1 B:THR32 4.4 16.2 1.0 OE1 B:GLN30 4.6 26.2 1.0 N B:CYS102 4.7 13.4 1.0 CA B:CYS102 4.7 15.7 1.0 C B:ASP100 4.9 12.7 1.0

H.Yoshida, M.Teraoka, N.Nishi, S.Kamitori. Crystal Structure of A Protease-Resistant Mutant Form of Human Galectin-9 To Be Published.