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Atomistry » Zinc » PDB 3wod-3wyl » 3ws9 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3wod-3wyl » 3ws9 » |
Zinc in PDB 3ws9: Crystal Structure of PDE10A in Complex with A Benzimdazole InhibitorEnzymatic activity of Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor
All present enzymatic activity of Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor, PDB code: 3ws9
was solved by
Y.Amano,
K.Honbou,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3ws9:
The structure of Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor
(pdb code 3ws9). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor, PDB code: 3ws9: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3ws9Go back to Zinc Binding Sites List in 3ws9
Zinc binding site 1 out
of 2 in the Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3ws9Go back to Zinc Binding Sites List in 3ws9
Zinc binding site 2 out
of 2 in the Crystal Structure of PDE10A in Complex with A Benzimdazole Inhibitor
Mono view Stereo pair view
Reference:
A.Chino,
N.Masuda,
Y.Amano,
K.Honbou,
T.Mihara,
M.Yamazaki,
M.Tomishima.
Novel Benzimidazole Derivatives As Phosphodiesterase 10A (PDE10A) Inhibitors with Improved Metabolic Stability. Bioorg.Med.Chem. 2014.
Page generated: Sat Oct 26 18:16:01 2024
ISSN: ESSN 1464-3391 PubMed: 24837154 DOI: 10.1016/J.BMC.2014.04.023 |
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