Zinc in PDB 3uyq: Hca 3

All present enzymatic activity of Hca 3:
4.2.1.1;

The structure of Hca 3, PDB code: 3uyq was solved by Z.Fisher, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.770, 50.780, 117.900, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 21.9

The binding sites of Zinc atom in the Hca 3 (pdb code 3uyq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Hca 3, PDB code: 3uyq:

Zinc binding site 1 out of 1 in the Hca 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Hca 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn261 b:11.9 occ:1.00 NE2 A:HIS96 2.1 7.7 1.0 ND1 A:HIS119 2.2 10.0 1.0 NE2 A:HIS94 2.2 11.6 1.0 O A:HOH271 2.7 11.8 1.0 CD2 A:HIS94 3.0 6.2 1.0 CE1 A:HIS119 3.0 9.8 1.0 CD2 A:HIS96 3.1 9.7 1.0 CE1 A:HIS96 3.1 9.3 1.0 CG A:HIS119 3.2 8.4 1.0 CE1 A:HIS94 3.3 7.0 1.0 CB A:HIS119 3.6 7.5 1.0 O A:HOH569 3.7 17.4 1.0 OG1 A:THR198 3.9 7.3 1.0 NE2 A:HIS119 4.2 7.7 1.0 CG A:HIS94 4.2 9.6 1.0 ND1 A:HIS96 4.2 10.3 1.0 OE1 A:GLU106 4.2 8.3 1.0 CG A:HIS96 4.2 10.8 1.0 CD2 A:HIS119 4.3 8.7 1.0 ND1 A:HIS94 4.3 11.2 1.0 O A:HOH393 4.6 18.7 1.0 O A:HOH470 4.7 15.7 1.0

I.Elder, Z.Fisher, P.J.Laipis, C.Tu, R.Mckenna, D.N.Silverman. Structural and Kinetic Analysis of Proton Shuttle Residues in the Active Site of Human Carbonic Anhydrase III. Proteins V. 68 337 2007.
ISSN: ISSN 0887-3585
PubMed: 17427958
DOI: 10.1002/PROT.21403