Zinc in PDB 3ux3: Crystal Structure of Domain-Swapped FAM96A Minor Dimer

The structure of Crystal Structure of Domain-Swapped FAM96A Minor Dimer, PDB code: 3ux3 was solved by K.-E.Chen, B.Kobe, J.L.Martin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.24 / 1.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	49.179, 52.246, 65.893, 90.00, 104.56, 90.00
R / Rfree (%)	20 / 24.6

The binding sites of Zinc atom in the Crystal Structure of Domain-Swapped FAM96A Minor Dimer (pdb code 3ux3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of Domain-Swapped FAM96A Minor Dimer, PDB code: 3ux3:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of Domain-Swapped FAM96A Minor Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Domain-Swapped FAM96A Minor Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:46.1 occ:1.00 SG B:CYS90 2.2 24.7 1.0 SG A:CYS90 2.2 23.7 1.0 OXT B:ACT1 2.3 58.8 1.0 O B:ACT1 2.7 57.7 1.0 HB3 A:CYS90 2.9 25.2 1.0 C B:ACT1 2.9 63.4 1.0 HB2 B:CYS90 3.0 27.6 1.0 CB B:CYS90 3.0 23.1 1.0 CB A:CYS90 3.0 21.1 1.0 HB3 B:CYS90 3.0 27.6 1.0 HB2 A:CYS90 3.1 25.2 1.0 HG B:SER124 3.1 33.1 1.0 OG B:SER124 3.2 27.7 1.0 OG A:SER124 3.5 23.4 1.0 HG A:SER124 3.5 27.9 1.0 HG1 A:THR122 4.1 29.0 1.0 HG1 B:THR122 4.2 32.0 1.0 HB2 B:SER124 4.3 30.8 1.0 HB2 A:SER124 4.3 25.8 1.0 CB B:SER124 4.3 25.8 1.0 CH3 B:ACT1 4.4 68.5 1.0 HA A:HIS123 4.4 20.3 1.0 HE21 B:GLN132 4.4 67.7 0.5 CA B:CYS90 4.4 21.2 1.0 CA A:CYS90 4.4 22.6 1.0 CB A:SER124 4.5 21.6 1.0 H B:CYS90 4.5 26.6 1.0 HA B:HIS123 4.5 24.0 1.0 H B:SER124 4.6 31.6 1.0 H A:CYS90 4.6 25.5 1.0 N B:SER124 4.6 26.5 1.0 HD13 B:ILE129 4.6 36.3 1.0 HA A:CYS90 4.7 26.9 1.0 HD13 A:ILE129 4.7 32.7 1.0 HE21 B:GLN132 4.8 49.5 0.5 H A:SER124 4.8 24.5 1.0 HA B:CYS90 4.8 25.3 1.0 N A:SER124 4.8 20.6 1.0 H1 B:ACT1 4.8 82.1 1.0 C B:HIS123 4.8 22.4 1.0 OG1 A:THR122 4.8 24.3 1.0 C A:HIS123 4.9 19.4 1.0 OG1 B:THR122 4.9 26.8 1.0 H2 B:ACT1 4.9 82.1 1.0 N B:CYS90 4.9 22.3 1.0 H3 B:ACT1 5.0 82.1 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of Domain-Swapped FAM96A Minor Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Domain-Swapped FAM96A Minor Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:33.9 occ:1.00 NE2 A:HIS123 2.1 27.7 1.0 NE2 A:HIS89 2.1 29.5 1.0 CD2 A:HIS89 2.9 26.0 1.0 HD2 A:HIS89 2.9 31.1 1.0 CE1 A:HIS123 3.0 26.2 1.0 HE1 A:HIS123 3.1 31.3 1.0 CD2 A:HIS123 3.1 26.7 1.0 CE1 A:HIS89 3.2 29.2 1.0 HD2 A:HIS123 3.4 31.9 1.0 HE1 A:HIS89 3.5 34.9 1.0 HG23 A:THR125 4.1 33.8 1.0 ND1 A:HIS123 4.1 25.4 1.0 CG A:HIS89 4.1 25.9 1.0 HD2 A:PRO88 4.2 33.3 1.0 CG A:HIS123 4.2 25.3 1.0 ND1 A:HIS89 4.3 31.0 1.0 HG22 A:THR125 4.3 33.8 1.0 HB A:VAL87 4.5 36.5 1.0 CG2 A:THR125 4.6 28.2 1.0 HG21 A:THR125 4.7 33.8 1.0 O A:HOH4 4.9 46.2 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of Domain-Swapped FAM96A Minor Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Domain-Swapped FAM96A Minor Dimer within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn158 b:34.3 occ:1.00 NE2 B:HIS123 2.0 25.8 1.0 NE2 B:HIS89 2.2 28.7 1.0 CE1 B:HIS123 2.9 25.6 1.0 HD2 B:HIS89 2.9 32.5 1.0 CD2 B:HIS89 2.9 27.2 1.0 HE1 B:HIS123 3.0 30.6 1.0 CD2 B:HIS123 3.0 28.1 1.0 HD2 B:HIS123 3.3 33.6 1.0 CE1 B:HIS89 3.4 34.9 1.0 HE1 B:HIS89 3.7 41.8 1.0 HD2 B:PRO88 3.9 36.4 1.0 ND1 B:HIS123 4.0 29.8 1.0 CG B:HIS123 4.1 24.9 1.0 CG B:HIS89 4.2 25.8 1.0 HB B:VAL87 4.3 38.2 1.0 HG23 B:THR125 4.3 50.5 1.0 ND1 B:HIS89 4.4 27.7 1.0 HG22 B:THR125 4.5 50.5 1.0 CG2 B:THR125 4.8 42.2 1.0 CD B:PRO88 4.8 30.5 1.0 HG21 B:THR125 4.9 50.5 1.0

K.E.Chen, A.A.Richards, J.K.Ariffin, I.L.Ross, M.J.Sweet, S.Kellie, B.Kobe, J.L.Martin. The Mammalian DUF59 Protein FAM96A Forms Two Distinct Types of Domain-Swapped Dimer. Acta Crystallogr.,Sect.D V. 68 637 2012.
ISSN: ESSN 1399-0047
PubMed: 22683786
DOI: 10.1107/S0907444912006592