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Atomistry » Zinc » PDB 3tg0-3ttr » 3tge » |
Zinc in PDB 3tge: A Novel Series of Potent and Selective PDE5 INHIBITOR1Enzymatic activity of A Novel Series of Potent and Selective PDE5 INHIBITOR1
All present enzymatic activity of A Novel Series of Potent and Selective PDE5 INHIBITOR1:
3.1.4.35; Protein crystallography data
The structure of A Novel Series of Potent and Selective PDE5 INHIBITOR1, PDB code: 3tge
was solved by
S.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3tge:
The structure of A Novel Series of Potent and Selective PDE5 INHIBITOR1 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the A Novel Series of Potent and Selective PDE5 INHIBITOR1
(pdb code 3tge). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the A Novel Series of Potent and Selective PDE5 INHIBITOR1, PDB code: 3tge: Zinc binding site 1 out of 1 in 3tgeGo back to Zinc Binding Sites List in 3tge
Zinc binding site 1 out
of 1 in the A Novel Series of Potent and Selective PDE5 INHIBITOR1
Mono view Stereo pair view
Reference:
R.O.Hughes,
T.Maddux,
D.Joseph Rogier,
S.Lu,
J.K.Walker,
E.Jon Jacobsen,
J.M.Rumsey,
Y.Zheng,
A.Macinnes,
B.R.Bond,
S.Han.
Investigation of the Pyrazinones As PDE5 Inhibitors: Evaluation of Regioisomeric Projections Into the Solvent Region. Bioorg.Med.Chem.Lett. V. 21 6348 2011.
Page generated: Wed Dec 16 04:52:16 2020
ISSN: ISSN 0960-894X PubMed: 21955943 DOI: 10.1016/J.BMCL.2011.08.106 |
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