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Atomistry » Zinc » PDB 3sci-3sjb » 3shz » |
Zinc in PDB 3shz: Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel InhibitorsEnzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
All present enzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors:
3.1.4.35; Protein crystallography data
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shz
was solved by
T.T.Chen,
T.Chen,
Y.C.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3shz:
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
(pdb code 3shz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shz: Zinc binding site 1 out of 1 in 3shzGo back to Zinc Binding Sites List in 3shz
Zinc binding site 1 out
of 1 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
Mono view Stereo pair view
Reference:
Z.Xu,
Z.Liu,
T.Chen,
T.T.Chen,
Z.Wang,
G.Tian,
J.Shi,
X.Wang,
Y.Lu,
X.Yan,
G.Wang,
H.Jiang,
K.Chen,
S.Wang,
Y.Xu,
J.Shen,
W.Zhu.
Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem. V. 54 5607 2011.
Page generated: Wed Dec 16 04:50:11 2020
ISSN: ISSN 0022-2623 PubMed: 21714539 DOI: 10.1021/JM200644R |
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