Atomistry » Zinc » PDB 3s2s-3scj » 3s2s
Atomistry »
  Zinc »
    PDB 3s2s-3scj »
      3s2s »

Zinc in PDB 3s2s: The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159

Enzymatic activity of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159

All present enzymatic activity of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159:
3.5.1.19;

Protein crystallography data

The structure of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159, PDB code: 3s2s was solved by X.-D.Su, X.Liu, H.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.98 / 1.70
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 76.490, 80.120, 130.960, 90.00, 90.00, 90.00
R / Rfree (%) 16 / 19.1

Other elements in 3s2s:

The structure of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 also contains other interesting chemical elements:

Arsenic (As) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 (pdb code 3s2s). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159, PDB code: 3s2s:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 3s2s

Go back to Zinc Binding Sites List in 3s2s
Zinc binding site 1 out of 4 in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn184

b:25.5
occ:0.80
 OD2 A:ASP53 2.0 28.4 1.0
OE1 A:GLU64 2.1 26.3 1.0
O A:HOH401 2.1 35.8 1.0
NE2 A:HIS55 2.2 25.9 1.0
NE2 A:HIS71 2.2 24.8 1.0
O A:HOH299 2.3 27.3 1.0
CD A:GLU64 3.0 26.4 1.0
CG A:ASP53 3.1 32.5 1.0
CE1 A:HIS71 3.1 27.2 1.0
CD2 A:HIS55 3.1 25.3 1.0
CE1 A:HIS55 3.1 27.9 1.0
OE2 A:GLU64 3.3 27.6 1.0
CD2 A:HIS71 3.3 24.3 1.0
OD1 A:ASP53 3.5 27.2 1.0
ND1 A:HIS71 4.2 25.2 1.0
ND1 A:HIS55 4.2 27.1 1.0
O A:HOH586 4.3 33.6 1.0
CG A:HIS55 4.3 25.0 1.0
CB A:ASP53 4.3 22.7 1.0
CG A:HIS71 4.4 26.9 1.0
CG A:GLU64 4.4 26.4 1.0
CZ A:PHE14 4.7 23.7 1.0
CE1 A:TYR106 4.8 20.8 1.0
O A:ARG104 5.0 17.3 1.0

Zinc binding site 2 out of 4 in 3s2s

Go back to Zinc Binding Sites List in 3s2s
Zinc binding site 2 out of 4 in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn184

b:29.1
occ:0.80
 O B:HOH216 2.0 24.8 1.0
OE1 B:GLU64 2.1 27.2 1.0
NE2 B:HIS71 2.2 29.1 1.0
NE2 B:HIS55 2.3 30.8 1.0
OD2 B:ASP53 2.3 30.7 1.0
OD1 B:ASP53 2.8 28.5 1.0
CG B:ASP53 2.8 27.5 1.0
CD B:GLU64 3.0 33.1 1.0
CE1 B:HIS71 3.1 27.2 1.0
CE1 B:HIS55 3.2 34.5 1.0
CD2 B:HIS71 3.2 25.4 1.0
CD2 B:HIS55 3.2 30.9 1.0
OE2 B:GLU64 3.2 34.4 1.0
O B:HOH307 4.1 33.8 1.0
O B:HOH306 4.1 29.8 1.0
ND1 B:HIS71 4.2 29.8 1.0
CB B:ASP53 4.3 23.0 1.0
CG B:HIS71 4.3 28.5 1.0
ND1 B:HIS55 4.3 34.3 1.0
CG B:HIS55 4.4 34.0 1.0
CG B:GLU64 4.4 25.9 1.0
O B:HOH224 4.5 28.3 1.0
CZ B:PHE14 4.6 30.2 1.0
CB B:GLU64 4.8 30.2 1.0

Zinc binding site 3 out of 4 in 3s2s

Go back to Zinc Binding Sites List in 3s2s
Zinc binding site 3 out of 4 in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn184

b:25.1
occ:0.60
 O C:HOH207 1.8 26.4 1.0
OE1 C:GLU64 2.2 26.2 1.0
NE2 C:HIS55 2.2 39.7 1.0
NE2 C:HIS71 2.2 31.2 1.0
OD2 C:ASP53 2.3 30.9 1.0
OD1 C:ASP53 2.8 31.0 1.0
CG C:ASP53 2.8 28.8 1.0
CE1 C:HIS55 3.0 46.4 1.0
CD C:GLU64 3.1 30.4 1.0
CE1 C:HIS71 3.1 27.2 1.0
CD2 C:HIS71 3.3 27.8 1.0
CD2 C:HIS55 3.3 32.8 1.0
OE2 C:GLU64 3.3 32.5 1.0
O C:HOH430 3.9 30.6 1.0
O C:HOH548 4.1 43.4 1.0
ND1 C:HIS71 4.2 30.5 1.0
ND1 C:HIS55 4.2 42.2 1.0
CB C:ASP53 4.3 20.7 1.0
CG C:HIS71 4.3 29.1 1.0
CG C:HIS55 4.4 31.4 1.0
O C:HOH225 4.4 30.8 1.0
CG C:GLU64 4.5 27.3 1.0
CZ C:PHE14 4.6 27.6 1.0
CB C:GLU64 4.9 35.5 1.0

Zinc binding site 4 out of 4 in 3s2s

Go back to Zinc Binding Sites List in 3s2s
Zinc binding site 4 out of 4 in the The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Crystal Structure of Pyrazinamidase/Nicotinamidase From Streptococcus Mutans UA159 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn184

b:28.1
occ:0.80
 O D:HOH204 1.9 24.4 1.0
OE1 D:GLU64 2.2 25.6 1.0
NE2 D:HIS71 2.2 29.7 1.0
NE2 D:HIS55 2.3 32.8 1.0
OD2 D:ASP53 2.3 32.6 1.0
OD1 D:ASP53 2.8 28.1 1.0
CG D:ASP53 2.8 27.3 1.0
CE1 D:HIS71 3.0 28.2 1.0
CD D:GLU64 3.1 27.5 1.0
CD2 D:HIS55 3.2 33.7 1.0
CD2 D:HIS71 3.2 28.5 1.0
CE1 D:HIS55 3.2 37.9 1.0
OE2 D:GLU64 3.3 31.1 1.0
ND1 D:HIS71 4.1 30.2 1.0
O D:HOH260 4.2 32.4 1.0
O D:HOH315 4.2 29.6 1.0
CB D:ASP53 4.3 21.2 1.0
CG D:HIS71 4.3 30.1 1.0
ND1 D:HIS55 4.4 36.3 1.0
CG D:HIS55 4.4 32.8 1.0
CZ D:PHE14 4.5 30.3 1.0
CG D:GLU64 4.5 27.3 1.0
O D:HOH218 4.5 27.8 1.0
CB D:GLU64 4.9 32.3 1.0
ND2 D:ASN72 5.0 34.2 1.0

Reference:

X.Liu, H.Zhang, X.J.Wang, L.F.Li, X.-D.Su. Get Phases From Arsenic Anomalous Scattering: De Novo Sad Phasing of Two Protein Structures Crystallized in Cacodylate Buffer Plos One V. 6 24227 2011.
ISSN: ESSN 1932-6203
PubMed: 21912678
DOI: 10.1371/JOURNAL.PONE.0024227
Page generated: Sat Oct 26 15:33:02 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy