Zinc in PDB 3rq4: Crystal Structure of Suppressor of Variegation 4-20 Homolog 2

All present enzymatic activity of Crystal Structure of Suppressor of Variegation 4-20 Homolog 2:
2.1.1.43;

The structure of Crystal Structure of Suppressor of Variegation 4-20 Homolog 2, PDB code: 3rq4 was solved by A.Dong, H.Zeng, W.Tempel, P.Loppnau, C.Bountra, J.Weigelt, C.H.Arrowsmith, A.M.Edwards, J.Min, H.Wu, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	34.680, 60.151, 126.601, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 22.1

The binding sites of Zinc atom in the Crystal Structure of Suppressor of Variegation 4-20 Homolog 2 (pdb code 3rq4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Suppressor of Variegation 4-20 Homolog 2, PDB code: 3rq4:

Zinc binding site 1 out of 1 in the Crystal Structure of Suppressor of Variegation 4-20 Homolog 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Suppressor of Variegation 4-20 Homolog 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1000 b:15.0 occ:1.00 SG A:CYS231 2.3 13.3 1.0 SG A:CYS234 2.3 17.1 1.0 SG A:CYS229 2.3 13.7 1.0 SG A:CYS185 2.4 15.2 1.0 CB A:CYS229 3.3 14.0 1.0 CB A:CYS234 3.4 16.1 1.0 CB A:CYS185 3.4 15.9 1.0 CB A:CYS231 3.4 12.6 1.0 N A:CYS185 3.9 13.5 1.0 N A:CYS234 4.1 16.8 1.0 N A:CYS231 4.1 13.4 1.0 CA A:CYS231 4.2 12.6 1.0 CA A:CYS185 4.3 14.6 1.0 CA A:CYS234 4.3 17.2 1.0 NE2 A:HIS183 4.4 13.2 1.0 O A:HOH384 4.5 26.0 1.0 CD2 A:HIS183 4.5 12.3 1.0 O A:HOH374 4.5 27.3 1.0 CA A:CYS229 4.6 13.8 1.0 O A:HOH278 4.6 29.8 1.0 C A:CYS229 4.6 13.8 1.0 C A:CYS231 4.8 13.2 1.0 O A:CYS229 4.8 13.7 1.0 O A:CYS231 4.9 13.8 1.0 C A:ASP184 4.9 12.5 1.0 N A:GLU230 5.0 13.4 1.0

H.Wu, A.Siarheyeva, H.Zeng, R.Lam, A.Dong, X.H.Wu, Y.Li, M.Schapira, M.Vedadi, J.Min. Crystal Structures of the Human Histone H4K20 Methyltransferases SUV420H1 and SUV420H2. Febs Lett. V. 587 3859 2013.
ISSN: ISSN 0014-5793
PubMed: 24396869