Zinc in PDB 3rld: Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II

All present enzymatic activity of Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II:
4.2.1.1;

The structure of Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II, PDB code: 3rld was solved by B.S.Avvaru, R.Mikulski, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.789, 41.598, 73.195, 90.00, 104.83, 90.00
R / Rfree (%)	16.6 / 21.1

The binding sites of Zinc atom in the Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II (pdb code 3rld). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II, PDB code: 3rld:

Zinc binding site 1 out of 1 in the Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Y7I Mutant of Human Carbonic Anhydrase II within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn262 b:11.7 occ:1.00 NE2 A:HIS96 2.0 12.4 1.0 NE2 A:HIS94 2.0 12.7 1.0 O A:HOH3013 2.0 14.5 1.0 ND1 A:HIS119 2.1 13.3 1.0 CD2 A:HIS94 2.9 11.6 1.0 CE1 A:HIS119 3.0 11.8 1.0 CD2 A:HIS96 3.0 12.2 1.0 CE1 A:HIS96 3.0 11.7 1.0 CE1 A:HIS94 3.1 14.1 1.0 CG A:HIS119 3.2 10.6 1.0 CB A:HIS119 3.6 11.0 1.0 O A:HOH3034 3.7 17.8 1.0 OG1 A:THR199 3.9 13.6 1.0 O A:HOH3163 3.9 42.2 1.0 OE1 A:GLU106 4.1 12.7 1.0 CG A:HIS94 4.1 9.7 1.0 NE2 A:HIS119 4.1 11.5 1.0 ND1 A:HIS94 4.2 12.5 1.0 ND1 A:HIS96 4.2 11.0 1.0 CG A:HIS96 4.2 12.3 1.0 CD2 A:HIS119 4.2 10.7 1.0 O A:HOH3015 4.3 16.7 1.0 CD A:GLU106 4.8 15.7 1.0 O A:HOH3069 5.0 24.0 1.0

R.Mikulski, B.S.Avvaru, C.Tu, N.Case, R.Mckenna, D.N.Silverman. Kinetic and Crystallographic Studies of the Role of Tyrosine 7 in the Active Site of Human Carbonic Anhydrase II. Arch.Biochem.Biophys. V. 506 181 2011.
ISSN: ISSN 0003-9861
PubMed: 21145876
DOI: 10.1016/J.ABB.2010.12.004