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Atomistry » Zinc » PDB 3qm3-3qz6 » 3qpp | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3qm3-3qz6 » 3qpp » |
Zinc in PDB 3qpp: Structure of PDE10-Inhibitor ComplexEnzymatic activity of Structure of PDE10-Inhibitor ComplexProtein crystallography data
The structure of Structure of PDE10-Inhibitor Complex, PDB code: 3qpp
was solved by
J.Pandit,
E.S.Marr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3qpp:
The structure of Structure of PDE10-Inhibitor Complex also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of PDE10-Inhibitor Complex
(pdb code 3qpp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of PDE10-Inhibitor Complex, PDB code: 3qpp: Zinc binding site 1 out of 1 in 3qppGo back to Zinc Binding Sites List in 3qpp
Zinc binding site 1 out
of 1 in the Structure of PDE10-Inhibitor Complex
Mono view Stereo pair view
Reference:
C.J.Helal,
Z.Kang,
X.Hou,
J.Pandit,
T.A.Chappie,
J.M.Humphrey,
E.S.Marr,
K.F.Fennell,
L.K.Chenard,
C.Fox,
C.J.Schmidt,
R.D.Williams,
D.S.Chapin,
J.Siuciak,
L.Lebel,
F.Menniti,
J.Cianfrogna,
K.R.Fonseca,
F.R.Nelson,
R.O'connor,
M.Macdougall,
L.Mcdowell,
S.Liras.
Use of Structure-Based Design to Discover A Potent, Selective, in Vivo Active Phosphodiesterase 10A Inhibitor Lead Series For the Treatment of Schizophrenia. J.Med.Chem. V. 54 4536 2011.
Page generated: Wed Dec 16 04:45:50 2020
ISSN: ISSN 0022-2623 PubMed: 21650160 DOI: 10.1021/JM2001508 |
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