Zinc in PDB 3py7: Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution

The structure of Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution, PDB code: 3py7 was solved by J.Cavarelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.95 / 2.29
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	105.051, 123.090, 94.594, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 22.5

The binding sites of Zinc atom in the Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution (pdb code 3py7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution, PDB code: 3py7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn524 b:35.0 occ:1.00 SG A:CYS510 1.9 35.3 1.0 SG A:CYS513 2.2 32.3 1.0 SG A:CYS479 2.4 32.0 1.0 SG A:CYS476 2.4 38.4 1.0 CB A:CYS513 3.1 40.1 1.0 CB A:CYS476 3.1 32.0 1.0 CB A:CYS510 3.4 31.2 1.0 CB A:CYS479 3.4 34.9 1.0 N A:CYS479 3.8 28.6 1.0 N A:CYS510 4.0 32.0 1.0 CA A:CYS479 4.2 35.0 1.0 CA A:CYS510 4.3 33.3 1.0 CA A:CYS513 4.3 38.1 1.0 N A:CYS513 4.3 33.5 1.0 CA A:CYS476 4.6 32.7 1.0 CB A:TYR478 4.7 35.3 1.0 C A:TYR478 4.8 34.1 1.0 C A:CYS510 4.9 34.5 1.0 O A:CYS510 4.9 30.5 1.0 C A:CYS479 4.9 36.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Full-Length Bovine Papillomavirus Oncoprotein E6 in Complex with LD1 Motif of Paxillin at 2.3A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn525 b:33.7 occ:1.00 SG A:CYS439 2.0 34.0 1.0 SG A:CYS436 2.2 32.9 1.0 SG A:CYS406 2.4 36.1 1.0 SG A:CYS403 2.5 35.0 1.0 CB A:CYS439 3.1 32.2 1.0 CB A:CYS403 3.2 35.7 1.0 CB A:CYS406 3.3 29.7 1.0 CB A:CYS436 3.5 32.8 1.0 N A:CYS406 3.7 33.6 1.0 N A:CYS436 4.1 34.6 1.0 CA A:CYS406 4.1 36.9 1.0 NE2 A:GLN356 4.1 39.7 1.0 N A:CYS439 4.2 28.5 1.0 CA A:CYS439 4.3 29.8 1.0 CA A:CYS436 4.3 33.2 1.0 O A:HOH655 4.4 46.5 1.0 CB A:TRP405 4.4 33.9 1.0 CA A:CYS403 4.7 36.3 1.0 C A:TRP405 4.8 35.4 1.0 O A:CYS436 4.8 37.0 1.0 C A:CYS436 4.9 37.1 1.0 C A:CYS406 4.9 40.1 1.0 CA A:TRP405 5.0 40.1 1.0

K.Zanier, S.Charbonnier, A.O.Sidi, A.G.Mcewen, M.G.Ferrario, P.Poussin-Courmontagne, V.Cura, N.Brimer, K.O.Babah, T.Ansari, I.Muller, R.H.Stote, J.Cavarelli, S.Vande Pol, G.Trave. Structural Basis For Hijacking of Cellular Lxxll Motifs By Papillomavirus E6 Oncoproteins. Science V. 339 694 2013.
ISSN: ISSN 0036-8075
PubMed: 23393263
DOI: 10.1126/SCIENCE.1229934