Zinc in PDB 3oy9: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution, PDB code: 3oy9 was solved by S.Hare, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.21 / 2.55
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	160.090, 160.090, 123.940, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 22.2

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution also contains other interesting chemical elements:

Manganese

(Mn)

3 atoms

The binding sites of Zinc atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution (pdb code 3oy9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution, PDB code: 3oy9:

Zinc binding site 1 out of 1 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese at 2.55 Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn393 b:45.1 occ:1.00 NE2 A:HIS62 2.0 40.8 1.0 ND1 A:HIS66 2.0 39.3 1.0 SG A:CYS99 2.4 43.4 1.0 SG A:CYS96 2.6 54.2 1.0 CE1 A:HIS62 2.8 41.9 1.0 CE1 A:HIS66 2.9 38.9 1.0 CG A:HIS66 3.0 41.7 1.0 CD2 A:HIS62 3.1 43.0 1.0 CB A:CYS99 3.3 45.0 1.0 CB A:HIS66 3.4 41.9 1.0 CB A:CYS96 3.7 54.5 1.0 N A:CYS99 3.7 45.8 1.0 CA A:HIS66 3.9 42.2 1.0 ND1 A:HIS62 4.0 42.7 1.0 CA A:CYS99 4.0 44.8 1.0 NE2 A:HIS66 4.0 40.5 1.0 CD2 A:HIS66 4.1 40.1 1.0 CG A:HIS62 4.1 44.3 1.0 O A:HOH449 4.4 55.6 1.0 C A:HIS66 4.5 42.5 1.0 O A:HIS66 4.6 42.8 1.0 C A:GLN98 4.7 47.4 1.0 CB A:GLN98 4.7 48.8 1.0 CA A:CYS96 5.0 54.4 1.0

S.Hare, S.S.Gupta, E.Valkov, A.Engelman, P.Cherepanov. Retroviral Intasome Assembly and Inhibition of Dna Strand Transfer. Nature V. 464 232 2010.
ISSN: ISSN 0028-0836
PubMed: 20118915
DOI: 10.1038/NATURE08784