Atomistry » Zinc » PDB 3o70-3okd » 3ohl
Atomistry »
  Zinc »
    PDB 3o70-3okd »
      3ohl »

Zinc in PDB 3ohl: Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide

Enzymatic activity of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide

All present enzymatic activity of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide:
3.4.24.17;

Protein crystallography data

The structure of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide, PDB code: 3ohl was solved by T.Kowatz, J.H.Naismith, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 23.31 / 2.36
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 56.964, 120.512, 46.627, 90.00, 90.00, 90.00
R / Rfree (%) 26.1 / 28.3

Other elements in 3ohl:

The structure of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide also contains other interesting chemical elements:

Calcium (Ca) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide (pdb code 3ohl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide, PDB code: 3ohl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3ohl

Go back to Zinc Binding Sites List in 3ohl
Zinc binding site 1 out of 2 in the Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4

b:43.8
occ:1.00
OD2 A:ASP153 2.0 39.6 1.0
O A:HOH12 2.1 0.0 1.0
NE2 A:HIS151 2.1 40.0 1.0
ND1 A:HIS179 2.1 41.7 1.0
NE2 A:HIS166 2.1 45.5 1.0
CG A:ASP153 3.1 41.3 1.0
CE1 A:HIS166 3.1 48.0 1.0
CD2 A:HIS151 3.1 39.5 1.0
CE1 A:HIS179 3.1 39.7 1.0
CE1 A:HIS151 3.1 40.7 1.0
CG A:HIS179 3.1 39.3 1.0
CD2 A:HIS166 3.2 45.9 1.0
CB A:HIS179 3.4 39.0 1.0
OD1 A:ASP153 3.4 43.0 1.0
ND1 A:HIS151 4.2 41.9 1.0
NE2 A:HIS179 4.2 39.8 1.0
ND1 A:HIS166 4.2 49.2 1.0
CG A:HIS151 4.2 39.7 1.0
CD2 A:HIS179 4.2 39.2 1.0
O A:TYR155 4.2 45.3 1.0
CG A:HIS166 4.3 46.5 1.0
OH A:TYR168 4.3 48.4 1.0
CB A:ASP153 4.4 43.0 1.0
CE1 A:TYR168 4.5 45.4 1.0
CZ A:PHE157 4.5 41.0 1.0
CE2 A:PHE157 4.5 40.9 1.0
CA A:HIS179 4.9 38.9 1.0
CZ A:TYR168 4.9 46.9 1.0

Zinc binding site 2 out of 2 in 3ohl

Go back to Zinc Binding Sites List in 3ohl
Zinc binding site 2 out of 2 in the Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Catalytic Domain of Stromelysin-1 in Complex with N-Hydroxy-2-(4- Methoxy-N-(Pyridine-3-Ylmethyl)Phenylsulfonamido)Acetamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn5

b:59.0
occ:1.00
O A:OHL6 2.0 74.0 1.0
OAE A:OHL6 2.0 62.3 1.0
NE2 A:HIS211 2.1 64.9 1.0
NE2 A:HIS205 2.1 57.6 1.0
NE2 A:HIS201 2.1 61.2 1.0
C A:OHL6 2.7 66.5 1.0
NAQ A:OHL6 2.7 61.6 1.0
CD2 A:HIS211 3.0 67.1 1.0
CD2 A:HIS201 3.0 59.5 1.0
CD2 A:HIS205 3.1 55.7 1.0
CE1 A:HIS205 3.1 58.9 1.0
CE1 A:HIS201 3.2 64.6 1.0
CE1 A:HIS211 3.2 67.3 1.0
CG A:HIS211 4.2 70.7 1.0
CG A:HIS201 4.2 60.4 1.0
CA A:OHL6 4.2 67.2 1.0
ND1 A:HIS205 4.2 57.3 1.0
ND1 A:HIS211 4.2 70.1 1.0
ND1 A:HIS201 4.2 63.7 1.0
CG A:HIS205 4.2 54.6 1.0
OE2 A:GLU202 4.2 47.5 1.0
N A:OHL6 4.8 72.0 1.0
OE1 A:GLU202 4.9 42.0 1.0
CAM A:OHL6 4.9 63.9 1.0
CD A:GLU202 4.9 46.2 1.0

Reference:

T.Kowatz, J.H.Naismith. Non-Resonance Raman Difference Spectroscopy As A Tool to Probe Enthalpy-Entropy Compensation and the Interfacial Mobility Model To Be Published.
Page generated: Sat Oct 26 10:55:55 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy