Zinc in PDB 3og8: Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna

All present enzymatic activity of Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna:
3.6.4.13;

The structure of Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna, PDB code: 3og8 was solved by P.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.96 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.990, 70.300, 125.540, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 27.8

The binding sites of Zinc atom in the Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna (pdb code 3og8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna, PDB code: 3og8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:18.5 occ:1.00 SG A:CYS869 2.3 24.9 1.0 SG A:CYS813 2.3 19.3 1.0 SG A:CYS864 2.4 16.7 1.0 SG A:CYS810 2.5 17.8 1.0 CB A:CYS864 3.1 20.2 1.0 CB A:CYS813 3.2 14.0 1.0 CB A:CYS810 3.2 12.6 1.0 CB A:CYS869 3.3 28.1 1.0 N A:CYS813 3.7 16.2 1.0 CA A:CYS813 4.0 18.6 1.0 CG A:ARG866 4.3 49.9 1.0 CB A:ARG866 4.4 46.3 1.0 CB A:HIS871 4.4 16.6 1.0 CZ2 A:TRP873 4.5 15.2 1.0 CB A:LYS812 4.6 17.8 1.0 CA A:CYS864 4.6 24.1 1.0 CA A:CYS810 4.7 15.9 1.0 CA A:CYS869 4.7 32.4 1.0 C A:CYS813 4.7 17.8 1.0 NE1 A:TRP873 4.7 18.3 1.0 C A:LYS812 4.8 15.2 1.0 N A:HIS871 4.8 19.2 1.0 N A:LYS814 4.8 18.5 1.0 N A:SER870 4.9 24.6 1.0 CE2 A:TRP873 5.0 17.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Rig-I Ctd Bound to A 14-Bp Blunt-Ended Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1 b:23.7 occ:1.00 SG B:CYS869 2.4 17.6 1.0 SG B:CYS864 2.4 27.0 1.0 SG B:CYS813 2.4 19.1 1.0 SG B:CYS810 2.5 21.0 1.0 CB B:CYS869 3.1 26.3 1.0 CB B:CYS864 3.1 25.3 1.0 CB B:CYS813 3.1 20.0 1.0 CB B:CYS810 3.4 19.8 1.0 N B:CYS813 3.7 23.6 1.0 CA B:CYS813 4.0 20.0 1.0 CB B:HIS871 4.4 18.4 1.0 CA B:CYS869 4.6 24.1 1.0 CB B:ARG866 4.6 36.2 1.0 CA B:CYS864 4.6 25.7 1.0 CZ2 B:TRP873 4.6 24.4 1.0 C B:LYS812 4.7 27.1 1.0 N B:HIS871 4.7 17.0 1.0 CB B:LYS812 4.7 29.6 1.0 C B:CYS813 4.8 20.0 1.0 NE1 B:TRP873 4.8 25.9 1.0 CA B:CYS810 4.8 19.9 1.0 N B:SER870 4.8 20.3 1.0 CD B:ARG866 4.9 50.8 1.0 C B:CYS869 5.0 23.8 1.0 N B:LYS814 5.0 20.3 1.0

C.Lu, C.T.Ranjith-Kumar, L.Hao, C.C.Kao, P.Li. Crystal Structure of Rig-I C-Terminal Domain Bound to Blunt-Ended Double-Strand Rna Without 5' Triphosphate. Nucleic Acids Res. V. 39 1565 2011.
ISSN: ISSN 0305-1048
PubMed: 20961956
DOI: 10.1093/NAR/GKQ974