Atomistry » Zinc » PDB 3nnq-3o64 » 3o37
Atomistry »
  Zinc »
    PDB 3nnq-3o64 »
      3o37 »

Zinc in PDB 3o37: Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide

Protein crystallography data

The structure of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide, PDB code: 3o37 was solved by Z.Wang, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.67 / 2.00
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 35.667, 63.848, 79.299, 89.92, 89.99, 89.80
R / Rfree (%) 22.7 / 25.4

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide (pdb code 3o37). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide, PDB code: 3o37:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 1 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1

b:46.5
occ:1.00
SG A:CYS870 2.3 42.1 1.0
SG A:CYS841 2.5 48.2 1.0
SG A:CYS867 2.5 35.8 1.0
SG A:CYS844 2.6 50.7 1.0
CB A:CYS844 3.2 53.9 1.0
CB A:CYS870 3.3 37.6 1.0
CB A:CYS841 3.5 51.2 1.0
N A:CYS844 3.7 55.5 1.0
CB A:CYS867 3.7 34.6 1.0
CA A:CYS844 4.0 53.6 1.0
N A:CYS870 4.0 33.4 1.0
N A:CYS867 4.1 36.8 1.0
CA A:CYS870 4.3 35.1 1.0
CA A:CYS867 4.3 35.4 1.0
C A:LYS843 4.4 57.9 1.0
CB A:LYS843 4.5 60.3 1.0
C A:CYS844 4.6 51.9 1.0
O A:CYS844 4.6 52.5 1.0
CB A:PHE869 4.7 32.2 1.0
O A:CYS867 4.7 31.6 1.0
C A:CYS867 4.7 33.4 1.0
N A:LYS843 4.8 57.6 1.0
CA A:LYS843 4.8 58.1 1.0
C A:PHE869 4.9 31.9 1.0
CA A:CYS841 4.9 53.8 1.0

Zinc binding site 2 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 2 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2

b:47.0
occ:1.00
ND1 A:HIS849 2.2 45.8 1.0
SG A:CYS829 2.3 41.1 1.0
SG A:CYS852 2.4 40.9 1.0
SG A:CYS832 2.5 41.3 1.0
CE1 A:HIS849 3.1 48.3 1.0
CB A:CYS829 3.1 47.9 1.0
CB A:CYS852 3.2 37.9 1.0
CG A:HIS849 3.2 47.3 1.0
CB A:CYS832 3.4 42.2 1.0
CB A:HIS849 3.6 44.1 1.0
N A:CYS832 3.6 41.2 1.0
CA A:CYS832 4.1 42.8 1.0
N A:HIS849 4.1 42.5 1.0
NE2 A:HIS849 4.2 50.8 1.0
CD2 A:HIS849 4.3 49.3 1.0
CA A:HIS849 4.5 43.2 1.0
CB A:VAL831 4.5 37.7 1.0
CA A:CYS829 4.6 47.2 1.0
CA A:CYS852 4.7 36.0 1.0
C A:VAL831 4.8 39.6 1.0
C A:CYS832 4.8 45.4 1.0
N A:GLN833 4.9 48.8 1.0

Zinc binding site 3 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 3 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1

b:45.4
occ:1.00
SG B:CYS829 2.2 42.2 1.0
ND1 B:HIS849 2.3 41.4 1.0
SG B:CYS852 2.4 42.3 1.0
SG B:CYS832 2.5 43.6 1.0
CB B:CYS829 3.0 46.8 1.0
CE1 B:HIS849 3.1 42.6 1.0
CB B:CYS852 3.1 37.5 1.0
CG B:HIS849 3.2 42.6 1.0
CB B:CYS832 3.5 43.2 1.0
CB B:HIS849 3.7 40.1 1.0
N B:CYS832 3.7 40.9 1.0
N B:HIS849 4.1 40.2 1.0
CA B:CYS832 4.1 43.3 1.0
NE2 B:HIS849 4.1 44.9 1.0
CD2 B:HIS849 4.2 43.6 1.0
CA B:CYS829 4.5 46.3 1.0
CB B:VAL831 4.5 35.8 1.0
CA B:HIS849 4.5 40.4 1.0
CA B:CYS852 4.6 33.7 1.0
C B:VAL831 4.8 38.8 1.0
C B:CYS832 4.9 45.8 1.0
C B:CYS829 4.9 43.5 1.0
N B:VAL831 4.9 37.1 1.0
N B:GLN833 4.9 48.8 1.0
CA B:VAL831 5.0 37.3 1.0

Zinc binding site 4 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 4 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2

b:49.6
occ:1.00
SG B:CYS870 2.2 39.1 1.0
SG B:CYS841 2.5 43.4 1.0
SG B:CYS867 2.5 33.1 1.0
SG B:CYS844 2.6 47.5 1.0
CB B:CYS844 3.1 48.6 1.0
CB B:CYS870 3.3 35.6 1.0
CB B:CYS841 3.5 47.4 1.0
CB B:CYS867 3.7 33.2 1.0
N B:CYS844 3.9 50.8 1.0
N B:CYS870 4.0 32.1 1.0
N B:CYS867 4.0 35.2 1.0
CA B:CYS844 4.1 49.2 1.0
CA B:CYS870 4.3 33.8 1.0
CA B:CYS867 4.3 33.4 1.0
C B:LYS843 4.5 53.8 1.0
O B:CYS867 4.6 31.4 1.0
O B:HOH149 4.6 37.1 1.0
C B:CYS844 4.6 47.0 1.0
CB B:PHE869 4.6 30.6 1.0
C B:CYS867 4.7 31.6 1.0
O B:CYS844 4.7 47.4 1.0
N B:LYS843 4.8 55.4 1.0
CA B:CYS841 4.9 51.4 1.0
CG B:LYS846 4.9 53.7 1.0
C B:PHE869 4.9 30.8 1.0
O B:LYS843 4.9 53.6 1.0

Zinc binding site 5 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 5 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn1

b:45.7
occ:1.00
ND1 C:HIS849 2.2 52.5 1.0
SG C:CYS829 2.4 43.1 1.0
SG C:CYS852 2.4 38.5 1.0
SG C:CYS832 2.5 42.4 1.0
CE1 C:HIS849 3.0 53.8 1.0
CB C:CYS829 3.1 47.3 1.0
CB C:CYS852 3.2 36.1 1.0
CG C:HIS849 3.3 51.6 1.0
CB C:CYS832 3.3 42.6 1.0
N C:CYS832 3.7 39.8 1.0
CB C:HIS849 3.7 47.9 1.0
CA C:CYS832 4.1 41.4 1.0
NE2 C:HIS849 4.2 55.7 1.0
N C:HIS849 4.3 44.2 1.0
CD2 C:HIS849 4.3 53.6 1.0
CA C:CYS829 4.6 45.9 1.0
CB C:VAL831 4.6 36.2 1.0
CA C:HIS849 4.6 45.0 1.0
CA C:CYS852 4.7 35.4 1.0
C C:VAL831 4.8 39.2 1.0
C C:CYS832 4.8 43.6 1.0
N C:GLN833 4.9 46.6 1.0

Zinc binding site 6 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 6 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn2

b:51.5
occ:1.00
SG C:CYS870 2.3 37.8 1.0
SG C:CYS867 2.5 34.6 1.0
SG C:CYS841 2.5 43.9 1.0
SG C:CYS844 2.5 48.7 1.0
CB C:CYS844 3.2 49.8 1.0
CB C:CYS870 3.4 35.0 1.0
CB C:CYS841 3.4 45.6 1.0
CB C:CYS867 3.5 34.8 1.0
N C:CYS844 3.8 51.0 1.0
CA C:CYS844 4.0 50.0 1.0
N C:CYS870 4.0 31.3 1.0
N C:CYS867 4.0 37.1 1.0
CA C:CYS867 4.3 34.5 1.0
CA C:CYS870 4.4 32.5 1.0
C C:LYS843 4.5 53.8 1.0
CB C:PHE869 4.6 30.4 1.0
C C:CYS844 4.6 48.6 1.0
O C:CYS867 4.7 31.3 1.0
C C:CYS867 4.7 32.3 1.0
CB C:LYS843 4.7 57.9 1.0
O C:CYS844 4.7 49.2 1.0
CA C:CYS841 4.8 49.0 1.0
CG2 C:ILE866 4.8 44.5 1.0
N C:LYS843 4.9 54.1 1.0
C C:PHE869 4.9 28.6 1.0
CA C:LYS843 5.0 54.2 1.0

Zinc binding site 7 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 7 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1

b:45.6
occ:1.00
ND1 D:HIS849 2.2 49.8 1.0
SG D:CYS829 2.3 43.2 1.0
SG D:CYS852 2.4 41.8 1.0
SG D:CYS832 2.5 44.9 1.0
CE1 D:HIS849 3.0 50.2 1.0
CB D:CYS829 3.1 49.3 1.0
CB D:CYS852 3.2 39.2 1.0
CG D:HIS849 3.2 49.4 1.0
CB D:CYS832 3.4 44.5 1.0
CB D:HIS849 3.6 46.2 1.0
N D:CYS832 3.7 42.3 1.0
N D:HIS849 4.1 43.3 1.0
CA D:CYS832 4.1 44.2 1.0
NE2 D:HIS849 4.1 52.1 1.0
CD2 D:HIS849 4.2 50.6 1.0
CA D:HIS849 4.5 44.2 1.0
CA D:CYS829 4.5 48.2 1.0
CB D:VAL831 4.6 39.6 1.0
CA D:CYS852 4.7 36.1 1.0
C D:VAL831 4.8 41.5 1.0
C D:CYS832 4.8 46.4 1.0
N D:GLN833 5.0 48.5 1.0

Zinc binding site 8 out of 8 in 3o37

Go back to Zinc Binding Sites List in 3o37
Zinc binding site 8 out of 8 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(1-10)K4 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2

b:47.0
occ:1.00
SG D:CYS870 2.3 43.2 1.0
SG D:CYS841 2.4 47.8 1.0
SG D:CYS867 2.5 36.4 1.0
SG D:CYS844 2.6 48.4 1.0
CB D:CYS844 3.1 49.6 1.0
CB D:CYS870 3.2 37.4 1.0
CB D:CYS841 3.4 51.5 1.0
CB D:CYS867 3.6 36.8 1.0
N D:CYS844 3.7 52.1 1.0
N D:CYS870 3.9 33.1 1.0
CA D:CYS844 4.0 49.4 1.0
N D:CYS867 4.0 37.4 1.0
CA D:CYS870 4.2 34.6 1.0
CA D:CYS867 4.3 35.0 1.0
C D:LYS843 4.4 55.4 1.0
CB D:LYS843 4.5 60.2 1.0
O D:CYS867 4.6 31.9 1.0
C D:CYS867 4.7 33.4 1.0
C D:CYS844 4.7 46.9 1.0
CB D:PHE869 4.7 30.9 1.0
CA D:LYS843 4.8 56.5 1.0
N D:LYS843 4.8 57.6 1.0
CA D:CYS841 4.8 55.1 1.0
CG2 D:ILE866 4.8 46.6 1.0
O D:CYS844 4.8 46.8 1.0
C D:PHE869 4.9 30.5 1.0

Reference:

W.W.Tsai, Z.Wang, T.T.Yiu, K.C.Akdemir, W.Xia, S.Winter, C.Y.Tsai, X.Shi, D.Schwarzer, W.Plunkett, B.Aronow, O.Gozani, W.Fischle, M.C.Hung, D.J.Patel, M.C.Barton. TRIM24 Links A Non-Canonical Histone Signature to Breast Cancer. Nature V. 468 927 2010.
ISSN: ISSN 0028-0836
PubMed: 21164480
DOI: 10.1038/NATURE09542
Page generated: Wed Dec 16 04:39:44 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy