Zinc in PDB 3o36: Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide

The structure of Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide, PDB code: 3o36 was solved by Z.Wang, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 1.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	89.754, 36.347, 126.963, 90.00, 109.67, 90.00
R / Rfree (%)	19.1 / 21.6

The binding sites of Zinc atom in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide (pdb code 3o36). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide, PDB code: 3o36:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:15.4 occ:1.00 ND1 A:HIS849 2.2 15.7 1.0 SG A:CYS852 2.3 15.9 1.0 SG A:CYS832 2.3 14.8 1.0 SG A:CYS829 2.4 13.1 1.0 CB A:CYS829 3.1 13.6 1.0 CE1 A:HIS849 3.2 18.0 1.0 CB A:CYS852 3.2 11.1 1.0 CG A:HIS849 3.2 17.1 1.0 CB A:CYS832 3.4 14.0 1.0 CB A:HIS849 3.5 16.0 1.0 N A:CYS832 3.8 16.2 1.0 N A:HIS849 4.1 13.6 1.0 CA A:CYS832 4.2 16.8 1.0 NE2 A:HIS849 4.3 17.8 1.0 CD2 A:HIS849 4.3 19.1 1.0 CA A:HIS849 4.4 13.6 1.0 CA A:CYS829 4.6 12.7 1.0 CB A:VAL831 4.6 12.2 1.0 CA A:CYS852 4.6 11.7 1.0 C A:VAL831 4.9 15.2 1.0 C A:CYS832 4.9 17.0 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:13.1 occ:1.00 SG A:CYS841 2.3 12.9 1.0 SG A:CYS844 2.4 13.5 1.0 SG A:CYS870 2.4 15.0 1.0 SG A:CYS867 2.4 12.1 1.0 CB A:CYS841 3.2 13.8 1.0 CB A:CYS844 3.3 16.1 1.0 CB A:CYS870 3.4 10.6 1.0 CB A:CYS867 3.5 10.7 1.0 N A:CYS844 3.7 16.2 1.0 CA A:CYS844 4.0 15.8 1.0 N A:CYS867 4.1 11.7 1.0 N A:CYS870 4.1 10.8 1.0 CA A:CYS867 4.3 9.4 1.0 CA A:CYS870 4.4 11.3 1.0 C A:LYS843 4.5 16.0 1.0 CB A:LYS843 4.6 21.4 1.0 C A:CYS844 4.7 15.6 1.0 CB A:PHE869 4.7 10.2 1.0 CA A:CYS841 4.7 14.0 1.0 O A:CYS844 4.7 15.2 1.0 O A:CYS867 4.7 8.6 1.0 C A:CYS867 4.8 8.9 1.0 N A:LYS843 4.9 16.2 1.0 CA A:LYS843 4.9 16.9 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1 b:20.1 occ:1.00 ND1 B:HIS849 2.2 26.6 1.0 SG B:CYS852 2.3 21.8 1.0 SG B:CYS832 2.4 20.8 1.0 SG B:CYS829 2.4 18.5 1.0 CB B:CYS829 3.1 18.6 1.0 CE1 B:HIS849 3.2 24.6 1.0 CG B:HIS849 3.2 23.5 1.0 CB B:CYS852 3.2 19.9 1.0 CB B:CYS832 3.4 18.7 1.0 CB B:HIS849 3.5 23.0 1.0 N B:CYS832 3.8 18.8 1.0 N B:HIS849 4.1 19.0 1.0 CA B:CYS832 4.2 19.0 1.0 NE2 B:HIS849 4.3 26.2 1.0 CD2 B:HIS849 4.3 23.2 1.0 CA B:HIS849 4.4 20.4 1.0 CA B:CYS829 4.6 20.2 1.0 CB B:VAL831 4.6 17.7 1.0 CA B:CYS852 4.6 16.0 1.0 C B:VAL831 4.8 20.8 1.0 C B:CYS832 4.9 19.9 1.0 N B:GLN833 5.0 19.0 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H4(14-19)K16AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:17.8 occ:1.00 SG B:CYS867 2.4 14.8 1.0 SG B:CYS870 2.4 16.8 1.0 SG B:CYS844 2.4 20.3 1.0 SG B:CYS841 2.4 18.7 1.0 CB B:CYS841 3.3 21.6 1.0 CB B:CYS870 3.3 15.2 1.0 CB B:CYS844 3.3 20.2 1.0 CB B:CYS867 3.5 13.0 1.0 N B:CYS844 3.8 19.2 1.0 N B:CYS867 4.1 15.3 1.0 N B:CYS870 4.1 14.9 1.0 CA B:CYS844 4.1 20.3 1.0 CA B:CYS867 4.3 13.9 1.0 CA B:CYS870 4.3 14.9 1.0 C B:LYS843 4.5 21.4 1.0 CB B:LYS843 4.6 26.7 1.0 C B:CYS844 4.7 19.5 1.0 O B:CYS867 4.7 13.5 1.0 CB B:PHE869 4.7 11.8 1.0 C B:CYS867 4.7 12.6 1.0 O B:CYS844 4.7 19.2 1.0 CA B:CYS841 4.8 20.6 1.0 N B:LYS843 4.9 22.6 1.0 CA B:LYS843 4.9 21.9 1.0 C B:PHE869 5.0 13.6 1.0

W.W.Tsai, Z.Wang, T.T.Yiu, K.C.Akdemir, W.Xia, S.Winter, C.Y.Tsai, X.Shi, D.Schwarzer, W.Plunkett, B.Aronow, O.Gozani, W.Fischle, M.C.Hung, D.J.Patel, M.C.Barton. TRIM24 Links A Non-Canonical Histone Signature to Breast Cancer. Nature V. 468 927 2010.
ISSN: ISSN 0028-0836
PubMed: 21164480
DOI: 10.1038/NATURE09542