Zinc in PDB 3o34: Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide

The structure of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide, PDB code: 3o34 was solved by Z.Wang, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.54 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.844, 41.107, 125.988, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 24.1

The binding sites of Zinc atom in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide (pdb code 3o34). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide, PDB code: 3o34:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:36.4 occ:1.00 ND1 A:HIS849 2.0 38.7 1.0 SG A:CYS852 2.3 30.4 1.0 SG A:CYS829 2.4 31.3 1.0 SG A:CYS832 2.4 43.5 1.0 CE1 A:HIS849 2.8 38.6 1.0 CB A:CYS829 3.0 36.4 1.0 CG A:HIS849 3.2 36.8 1.0 CB A:CYS852 3.2 28.0 1.0 CB A:CYS832 3.2 45.1 1.0 N A:CYS832 3.6 41.6 1.0 CB A:HIS849 3.6 33.4 1.0 CA A:CYS832 3.9 45.1 1.0 NE2 A:HIS849 4.0 39.7 1.0 CD2 A:HIS849 4.2 37.1 1.0 N A:HIS849 4.2 31.4 1.0 CA A:CYS829 4.5 40.1 1.0 CA A:HIS849 4.6 32.0 1.0 N A:GLN833 4.6 51.4 1.0 CA A:CYS852 4.6 25.3 1.0 CB A:VAL831 4.6 35.6 1.0 C A:CYS832 4.6 47.7 1.0 C A:VAL831 4.8 38.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of TRIM24 Phd-Bromo Complexed with H3(13-32)K23AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:36.2 occ:1.00 SG A:CYS870 2.4 28.9 1.0 SG A:CYS867 2.4 24.4 1.0 SG A:CYS841 2.5 33.8 1.0 SG A:CYS844 2.5 35.4 1.0 CB A:CYS844 3.2 41.5 1.0 CB A:CYS841 3.3 35.0 1.0 CB A:CYS867 3.4 27.9 1.0 CB A:CYS870 3.5 28.9 1.0 N A:CYS844 3.7 44.9 1.0 N A:CYS867 3.9 32.4 1.0 CA A:CYS844 4.0 43.1 1.0 CA A:CYS867 4.2 28.1 1.0 N A:CYS870 4.2 26.5 1.0 CA A:CYS870 4.5 27.6 1.0 C A:LYS843 4.5 47.8 1.0 O A:CYS867 4.7 23.9 1.0 C A:CYS867 4.7 25.5 1.0 C A:CYS844 4.7 41.8 1.0 CB A:LYS843 4.7 49.1 1.0 CA A:CYS841 4.7 39.5 1.0 O A:CYS844 4.8 41.8 1.0 CB A:PHE869 4.8 22.2 1.0 N A:LYS843 4.9 50.2 1.0 CA A:LYS843 4.9 48.7 1.0

W.W.Tsai, Z.Wang, T.T.Yiu, K.C.Akdemir, W.Xia, S.Winter, C.Y.Tsai, X.Shi, D.Schwarzer, W.Plunkett, B.Aronow, O.Gozani, W.Fischle, M.C.Hung, D.J.Patel, M.C.Barton. TRIM24 Links A Non-Canonical Histone Signature to Breast Cancer. Nature V. 468 927 2010.
ISSN: ISSN 0028-0836
PubMed: 21164480
DOI: 10.1038/NATURE09542