Zinc in PDB 3o0m: Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis

The structure of Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis, PDB code: 3o0m was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.27 / 1.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	59.150, 63.520, 76.500, 90.00, 100.51, 90.00
R / Rfree (%)	15.7 / 19.1

The binding sites of Zinc atom in the Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis (pdb code 3o0m). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis, PDB code: 3o0m:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn151 b:18.7 occ:1.00 ND1 A:HIS97 2.1 10.7 1.0 ND1 A:HIS45 2.1 13.8 1.0 SG A:CYS3 2.2 11.7 1.0 SG A:CYS6 2.3 11.9 1.0 CE1 A:HIS97 3.0 11.8 1.0 CE1 A:HIS45 3.0 15.6 1.0 CG A:HIS97 3.1 10.4 1.0 CG A:HIS45 3.1 15.1 1.0 CB A:CYS3 3.2 13.1 1.0 CB A:CYS6 3.4 11.1 1.0 CB A:HIS97 3.4 9.3 1.0 N A:CYS6 3.4 9.8 1.0 CB A:HIS45 3.5 14.5 1.0 CA A:CYS6 3.8 10.2 1.0 NE2 A:HIS97 4.1 9.7 1.0 NE2 A:HIS45 4.2 16.2 1.0 CD2 A:HIS97 4.2 9.3 1.0 CD2 A:HIS45 4.3 16.0 1.0 CA A:HIS45 4.3 13.9 1.0 C A:PHE5 4.4 9.2 1.0 CB A:PHE5 4.6 9.2 1.0 CA A:CYS3 4.6 13.7 1.0 O A:HOH271 4.6 16.3 1.0 CA A:HIS97 4.6 9.6 1.0 O A:HOH213 4.7 13.3 1.0 O A:CYS3 4.9 13.1 1.0 CA A:PHE5 4.9 9.5 1.0 C A:CYS3 4.9 13.2 1.0 N A:PHE5 4.9 10.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of A Zn-Bound Histidine Triad Family Protein From Mycobacterium Smegmatis within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn151 b:21.5 occ:1.00 ND1 B:HIS45 2.1 16.3 1.0 SG B:CYS3 2.2 14.4 1.0 ND1 B:HIS97 2.2 11.9 1.0 SG B:CYS6 2.3 14.7 1.0 CE1 B:HIS45 3.0 16.1 1.0 CB B:CYS3 3.1 18.7 1.0 CE1 B:HIS97 3.1 12.9 1.0 CG B:HIS97 3.1 11.8 1.0 CG B:HIS45 3.2 16.0 1.0 CB B:CYS6 3.3 15.7 1.0 CB B:HIS97 3.4 12.4 1.0 N B:CYS6 3.5 14.0 1.0 CB B:HIS45 3.6 15.3 1.0 CA B:CYS6 3.8 14.6 1.0 NE2 B:HIS45 4.1 15.7 1.0 NE2 B:HIS97 4.2 11.5 1.0 CD2 B:HIS45 4.3 16.9 1.0 CD2 B:HIS97 4.3 11.7 1.0 CA B:HIS45 4.3 15.0 1.0 C B:PHE5 4.4 13.6 1.0 CA B:CYS3 4.5 19.3 1.0 CA B:HIS97 4.6 12.3 1.0 CB B:PHE5 4.6 13.0 1.0 O B:HOH177 4.8 20.6 1.0 O B:CYS3 4.8 18.1 1.0 C B:CYS3 4.8 18.5 1.0 CA B:PHE5 4.9 13.1 1.0 N B:PHE5 5.0 14.5 1.0

L.Baugh, I.Phan, D.W.Begley, M.C.Clifton, B.Armour, D.M.Dranow, B.M.Taylor, M.M.Muruthi, J.Abendroth, J.W.Fairman, D.Fox, S.H.Dieterich, B.L.Staker, A.S.Gardberg, R.Choi, S.N.Hewitt, A.J.Napuli, J.Myers, L.K.Barrett, Y.Zhang, M.Ferrell, E.Mundt, K.Thompkins, N.Tran, S.Lyons-Abbott, A.Abramov, A.Sekar, D.Serbzhinskiy, D.Lorimer, G.W.Buchko, R.Stacy, L.J.Stewart, T.E.Edwards, W.C.Van Voorhis, P.J.Myler. Increasing the Structural Coverage of Tuberculosis Drug Targets. Tuberculosis (Edinb) V. 95 142 2015.
ISSN: ISSN 1472-9792
PubMed: 25613812
DOI: 10.1016/J.TUBE.2014.12.003