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Atomistry » Zinc » PDB 3nik-3nny » 3nlg » |
Zinc in PDB 3nlg: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-AmineEnzymatic activity of Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
All present enzymatic activity of Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine, PDB code: 3nlg
was solved by
H.Ji,
S.L.Delker,
H.Li,
P.Martasek,
L.Roman,
T.L.Poulos,
R.B.Silverman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3nlg:
The structure of Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
(pdb code 3nlg). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine, PDB code: 3nlg: Zinc binding site 1 out of 1 in 3nlgGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'S,4'R)-3'-[2"-(3'''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.Ji,
S.L.Delker,
H.Li,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Exploration of the Active Site of Neuronal Nitric Oxide Synthase By the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives. J.Med.Chem. V. 53 7804 2010.
Page generated: Sat Oct 26 10:26:43 2024
ISSN: ISSN 0022-2623 PubMed: 20958055 DOI: 10.1021/JM100947X |
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