Atomistry » Zinc » PDB 3avr-3b6n » 3mwo
Atomistry »
  Zinc »
    PDB 3avr-3b6n »
      3mwo »

Zinc in PDB 3mwo: Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination

Enzymatic activity of Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination

All present enzymatic activity of Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination, PDB code: 3mwo was solved by A.H.Robbins, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 18.28 / 1.40
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 83.981, 41.057, 73.586, 90.00, 109.33, 90.00
R / Rfree (%) 16.6 / 18.4

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination (pdb code 3mwo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination, PDB code: 3mwo:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3mwo

Go back to Zinc Binding Sites List in 3mwo
Zinc binding site 1 out of 2 in the Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn262

b:6.4
occ:1.00
O A:HOH263 1.9 6.7 1.0
NE2 A:HIS96 2.0 5.9 1.0
NE2 A:HIS94 2.0 5.3 1.0
ND1 A:HIS119 2.1 6.0 1.0
CE1 A:HIS119 2.9 5.3 1.0
CD2 A:HIS94 3.0 7.6 1.0
HE1 A:HIS119 3.0 6.4 1.0
CE1 A:HIS96 3.0 8.1 1.0
CD2 A:HIS96 3.0 5.7 1.0
CE1 A:HIS94 3.1 6.1 1.0
HD2 A:HIS94 3.1 9.1 1.0
HE1 A:HIS96 3.2 9.8 1.0
CG A:HIS119 3.2 4.9 1.0
HD2 A:HIS96 3.2 6.8 1.0
HB2 A:HIS119 3.2 7.5 1.0
HE1 A:HIS94 3.3 7.4 1.0
HG1 A:THR199 3.5 7.8 1.0
CB A:HIS119 3.6 6.2 1.0
O A:HOH267 3.7 11.5 1.0
OG1 A:THR199 3.8 6.5 1.0
HB3 A:HIS119 3.8 7.5 1.0
OE1 A:GLU106 4.0 6.6 1.0
NE2 A:HIS119 4.1 5.5 1.0
O A:HOH353 4.1 16.0 1.0
ND1 A:HIS96 4.1 7.2 1.0
CG A:HIS94 4.1 5.6 1.0
ND1 A:HIS94 4.1 6.4 1.0
CG A:HIS96 4.1 5.3 1.0
CD2 A:HIS119 4.2 5.7 1.0
HH2 A:TRP209 4.3 6.8 1.0
O A:HOH316 4.4 15.3 1.0
HG23 A:THR200 4.8 11.2 1.0
HE2 A:HIS119 4.8 6.6 1.0
CD A:GLU106 4.8 6.9 1.0
HD1 A:HIS96 4.9 8.7 1.0
HD1 A:HIS94 4.9 7.7 1.0
H A:THR199 5.0 8.0 1.0

Zinc binding site 2 out of 2 in 3mwo

Go back to Zinc Binding Sites List in 3mwo
Zinc binding site 2 out of 2 in the Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Carbonic Anhydrase II in A Doubled Monoclinic Cell: A Re- Determination within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn262

b:5.5
occ:1.00
O B:HOH269 1.9 6.5 1.0
NE2 B:HIS96 2.0 5.2 1.0
NE2 B:HIS94 2.0 4.5 1.0
ND1 B:HIS119 2.0 5.3 1.0
CE1 B:HIS119 2.9 4.6 1.0
CD2 B:HIS94 3.0 5.9 1.0
CE1 B:HIS96 3.0 6.4 1.0
HE1 B:HIS119 3.0 5.5 1.0
CD2 B:HIS96 3.0 6.0 1.0
CE1 B:HIS94 3.1 4.3 1.0
HD2 B:HIS94 3.1 7.1 1.0
CG B:HIS119 3.2 4.8 1.0
HE1 B:HIS96 3.2 7.7 1.0
HD2 B:HIS96 3.2 7.2 1.0
HB2 B:HIS119 3.2 6.5 1.0
HE1 B:HIS94 3.3 5.1 1.0
HG1 B:THR199 3.5 7.0 1.0
CB B:HIS119 3.6 5.4 1.0
O B:HOH284 3.7 9.8 1.0
HB3 B:HIS119 3.8 6.5 1.0
OG1 B:THR199 3.8 5.8 1.0
OE1 B:GLU106 4.0 6.6 1.0
NE2 B:HIS119 4.1 5.1 1.0
O B:HOH396 4.1 16.9 1.0
ND1 B:HIS96 4.1 6.1 1.0
CG B:HIS94 4.1 5.7 1.0
CG B:HIS96 4.1 5.1 1.0
ND1 B:HIS94 4.2 5.5 1.0
CD2 B:HIS119 4.2 5.4 1.0
HH2 B:TRP209 4.2 6.8 1.0
O B:HOH335 4.4 12.6 1.0
HE2 B:HIS119 4.8 6.2 1.0
CD B:GLU106 4.9 6.8 1.0
HD1 B:HIS96 4.9 7.3 1.0
HD1 B:HIS94 4.9 6.6 1.0
HG23 B:THR200 4.9 9.7 1.0

Reference:

A.H.Robbins, J.F.Domsic, M.Agbandje-Mckenna, R.Mckenna. Emerging From Pseudo-Symmetry: the Redetermination of Human Carbonic Anhydrase II in Monoclinic P2(1) with A Doubled A Axis. Acta Crystallogr.,Sect.D V. 66 950 2010.
ISSN: ISSN 0907-4449
PubMed: 20693695
DOI: 10.1107/S0907444910023723
Page generated: Sat Sep 26 11:51:05 2020
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy