Atomistry » Zinc » PDB 3mhs-3mpu » 3mnh
Atomistry »
  Zinc »
    PDB 3mhs-3mpu »
      3mnh »

Zinc in PDB 3mnh: Human Carbonic Anhydrase II Mutant K170A

Enzymatic activity of Human Carbonic Anhydrase II Mutant K170A

All present enzymatic activity of Human Carbonic Anhydrase II Mutant K170A:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II Mutant K170A, PDB code: 3mnh was solved by J.F.Domsic, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.78 / 1.65
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.645, 41.564, 72.750, 90.00, 104.50, 90.00
R / Rfree (%) 15.5 / 18.8

Other elements in 3mnh:

The structure of Human Carbonic Anhydrase II Mutant K170A also contains other interesting chemical elements:

Sodium (Na) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase II Mutant K170A (pdb code 3mnh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II Mutant K170A, PDB code: 3mnh:

Zinc binding site 1 out of 1 in 3mnh

Go back to Zinc Binding Sites List in 3mnh
Zinc binding site 1 out of 1 in the Human Carbonic Anhydrase II Mutant K170A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase II Mutant K170A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn262

b:8.8
occ:1.00
NE2 A:HIS94 2.0 8.5 1.0
NE2 A:HIS96 2.0 5.7 1.0
ND1 A:HIS119 2.0 7.7 1.0
O A:HOH316 2.0 12.7 1.0
CE1 A:HIS119 2.9 5.0 1.0
CD2 A:HIS94 3.0 7.8 1.0
CD2 A:HIS96 3.0 8.3 1.0
CE1 A:HIS94 3.0 10.7 1.0
CE1 A:HIS96 3.0 9.6 1.0
CG A:HIS119 3.1 5.9 1.0
CB A:HIS119 3.6 5.4 1.0
O A:HOH347 3.8 22.3 1.0
OG1 A:THR199 3.9 10.4 1.0
O A:HOH420 4.0 28.6 1.0
OE1 A:GLU106 4.1 10.5 1.0
NE2 A:HIS119 4.1 5.7 1.0
CG A:HIS94 4.1 7.8 1.0
ND1 A:HIS94 4.1 9.6 1.0
CG A:HIS96 4.1 6.6 1.0
ND1 A:HIS96 4.2 9.2 1.0
O A:HOH324 4.2 18.8 1.0
CD2 A:HIS119 4.2 6.0 1.0
CD A:GLU106 4.9 13.3 1.0

Reference:

J.F.Domsic, W.Williams, S.Z.Fisher, C.Tu, M.Agbandje-Mckenna, D.N.Silverman, R.Mckenna. Structural and Kinetic Study of the Extended Active Site For Proton Transfer in Human Carbonic Anhydrase II. Biochemistry V. 49 6394 2010.
ISSN: ISSN 0006-2960
PubMed: 20578724
DOI: 10.1021/BI1007645
Page generated: Wed Dec 16 04:35:43 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy