Zinc in PDB 3lmh: Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp

All present enzymatic activity of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp:
2.7.11.7;

The structure of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp, PDB code: 3lmh was solved by Q.Ye, Z.Jia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.70 / 2.00
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	82.824, 110.047, 78.714, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 25.9

The binding sites of Zinc atom in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp (pdb code 3lmh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp, PDB code: 3lmh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:27.3 occ:1.00 CE1 A:HIS794 1.9 22.1 1.0 ND1 A:HIS742 2.1 23.2 1.0 SG A:CYS800 2.4 26.8 1.0 SG A:CYS796 2.4 31.9 1.0 NE2 A:HIS794 2.7 27.4 1.0 ND1 A:HIS794 3.1 27.9 1.0 CG A:HIS742 3.1 21.5 1.0 CE1 A:HIS742 3.1 24.0 1.0 CB A:CYS800 3.2 26.3 1.0 CB A:CYS796 3.4 32.8 1.0 CB A:HIS742 3.4 18.3 1.0 CA A:CYS796 3.4 32.5 1.0 CD2 A:HIS794 4.0 25.2 1.0 CG A:HIS794 4.1 28.1 1.0 N A:CYS796 4.2 33.0 1.0 NE2 A:HIS742 4.2 23.4 1.0 CD2 A:HIS742 4.2 20.6 1.0 O A:HOH159 4.5 39.2 1.0 CA A:CYS800 4.5 27.0 1.0 N A:ASN797 4.5 31.6 1.0 C A:CYS796 4.6 32.6 1.0 CD1 A:LEU805 4.7 28.2 1.0 O A:LYS795 4.7 33.9 1.0 C A:LYS795 4.7 33.3 1.0 CA A:HIS742 4.9 17.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:27.3 occ:1.00 SG B:CYS800 2.0 29.1 1.0 CE1 B:HIS794 2.1 35.0 1.0 CD2 B:HIS742 2.2 24.2 1.0 CG B:HIS742 3.0 22.7 1.0 NE2 B:HIS794 3.0 36.0 1.0 CB B:CYS796 3.1 42.7 1.0 ND1 B:HIS794 3.1 37.4 1.0 CB B:CYS800 3.2 31.6 1.0 NE2 B:HIS742 3.2 25.0 1.0 CA B:CYS796 3.4 42.5 1.0 CB B:HIS742 3.4 19.9 1.0 ND1 B:HIS742 4.1 27.3 1.0 N B:CYS796 4.1 42.2 1.0 CE1 B:HIS742 4.2 25.6 1.0 CD2 B:HIS794 4.2 36.3 1.0 CG B:HIS794 4.3 38.0 1.0 CA B:CYS800 4.5 31.6 1.0 O B:HOH140 4.5 33.9 1.0 C B:CYS796 4.5 41.2 1.0 N B:ASN797 4.6 39.5 1.0 CD1 B:LEU805 4.7 33.5 1.0 C B:LYS795 4.7 42.2 1.0 O B:LYS795 4.8 42.0 1.0 SG B:CYS796 4.8 49.8 1.0 CA B:HIS742 5.0 19.7 1.0

Q.Ye, S.W.Crawley, Y.Yang, G.P.Cote, Z.Jia. Crystal Structure of the {Alpha}-Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A. Sci.Signal. V. 3 RA17 2010.
ISSN: ESSN 1937-9145
PubMed: 20197546
DOI: 10.1126/SCISIGNAL.2000525