Zinc in PDB 3lla: Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp

All present enzymatic activity of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp:
2.7.11.7;

The structure of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp, PDB code: 3lla was solved by Q.Ye, Z.Jia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.90 / 2.11
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.075, 109.808, 79.626, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 26.3

The binding sites of Zinc atom in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp (pdb code 3lla). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp, PDB code: 3lla:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2002 b:23.6 occ:1.00 NE2 A:HIS794 1.9 16.1 1.0 ND1 A:HIS742 2.1 17.6 1.0 SG A:CYS800 2.4 26.1 1.0 SG A:CYS796 2.4 28.9 1.0 CD2 A:HIS794 2.9 21.6 1.0 CE1 A:HIS794 2.9 21.1 1.0 CE1 A:HIS742 3.0 19.0 1.0 CG A:HIS742 3.1 17.3 1.0 CB A:CYS800 3.2 24.1 1.0 CB A:CYS796 3.4 29.4 1.0 CA A:CYS796 3.4 29.1 1.0 CB A:HIS742 3.5 15.2 1.0 ND1 A:HIS794 4.0 20.0 1.0 CG A:HIS794 4.0 23.4 1.0 NE2 A:HIS742 4.2 18.5 1.0 N A:CYS796 4.2 29.4 1.0 CD2 A:HIS742 4.2 18.2 1.0 CA A:CYS800 4.5 25.0 1.0 O A:HOH213 4.5 34.4 1.0 C A:CYS796 4.6 28.8 1.0 N A:ASN797 4.6 27.5 1.0 CD1 A:LEU805 4.6 25.1 1.0 O A:LYS795 4.8 30.8 1.0 C A:LYS795 4.8 30.2 1.0 O A:HOH152 4.9 31.3 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Alpha-Kinase Domain of Myosin Heavy Chain Kinase A Complex with Amppcp within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2001 b:23.4 occ:1.00 ND1 B:HIS742 1.7 21.0 1.0 SG B:CYS800 2.0 24.5 1.0 NE2 B:HIS794 2.1 26.2 1.0 CE1 B:HIS742 2.6 21.3 1.0 CB B:CYS796 2.9 35.6 1.0 CG B:HIS742 2.9 19.0 1.0 CE1 B:HIS794 3.1 25.1 1.0 CD2 B:HIS794 3.1 25.0 1.0 CA B:CYS796 3.2 35.3 1.0 CB B:CYS800 3.3 26.6 1.0 CB B:HIS742 3.4 16.2 1.0 NE2 B:HIS742 3.7 20.8 1.0 CD2 B:HIS742 3.9 20.2 1.0 N B:CYS796 4.1 34.3 1.0 ND1 B:HIS794 4.2 24.8 1.0 CG B:HIS794 4.3 27.2 1.0 C B:CYS796 4.4 33.9 1.0 N B:ASN797 4.5 32.0 1.0 CA B:CYS800 4.5 26.2 1.0 SG B:CYS796 4.5 45.8 1.0 O B:HOH136 4.6 33.8 1.0 CD1 B:LEU805 4.6 28.1 1.0 C B:LYS795 4.7 34.0 1.0 O B:LYS795 4.7 34.1 1.0 CA B:HIS742 5.0 16.3 1.0

Q.Ye, S.W.Crawley, Y.Yang, G.P.Cote, Z.Jia. Crystal Structure of the {Alpha}-Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A. Sci.Signal. V. 3 RA17 2010.
ISSN: ESSN 1937-9145
PubMed: 20197546
DOI: 10.1126/SCISIGNAL.2000525