Zinc in PDB 3l2q: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form

Protein crystallography data

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form, PDB code: 3l2q was solved by S.Hare, S.S.Gupta, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.38 / 3.25
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 158.250, 158.250, 124.750, 90.00, 90.00, 90.00
R / Rfree (%) 19.7 / 22.1

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form (pdb code 3l2q). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form, PDB code: 3l2q:

Zinc binding site 1 out of 1 in 3l2q

Go back to Zinc Binding Sites List in 3l2q
Zinc binding site 1 out of 1 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Apo Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn393

b:76.2
occ:1.00
NE2 A:HIS62 2.0 78.2 1.0
ND1 A:HIS66 2.0 82.1 1.0
SG A:CYS99 2.2 79.2 1.0
SG A:CYS96 2.2 88.7 1.0
CE1 A:HIS62 2.9 77.1 1.0
CE1 A:HIS66 3.0 84.7 1.0
CG A:HIS66 3.0 81.6 1.0
CD2 A:HIS62 3.0 79.3 1.0
CB A:HIS66 3.4 80.2 1.0
CB A:CYS96 3.4 88.4 1.0
CB A:CYS99 3.5 79.3 1.0
N A:CYS99 3.9 82.5 1.0
CA A:HIS66 3.9 79.7 1.0
ND1 A:HIS62 4.1 77.0 1.0
NE2 A:HIS66 4.1 85.1 1.0
CD2 A:HIS66 4.1 83.1 1.0
CG A:HIS62 4.1 79.1 1.0
CA A:CYS99 4.2 80.2 1.0
C A:HIS66 4.5 78.5 1.0
O A:HIS66 4.5 78.4 1.0
OD1 A:ASN63 4.7 84.6 1.0
CB A:GLN98 4.8 87.9 1.0
CA A:CYS96 4.8 90.7 1.0
C A:GLN98 4.9 84.4 1.0

Reference:

S.Hare, S.S.Gupta, E.Valkov, A.Engelman, P.Cherepanov. Retroviral Intasome Assembly and Inhibition of Dna Strand Transfer Nature V. 464 232 2010.
ISSN: ISSN 0028-0836
PubMed: 20118915
DOI: 10.1038/NATURE08784
Page generated: Wed Dec 16 04:31:44 2020

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