Zinc in PDB 3ivb: Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1

The structure of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1, PDB code: 3ivb was solved by B.A.Schulman, D.J.Miller, M.F.Calabrese, S.Seyedin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.74 / 1.75
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	44.021, 44.021, 266.840, 90.00, 90.00, 120.00
R / Rfree (%)	21.8 / 24.7

The structure of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 (pdb code 3ivb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1, PDB code: 3ivb:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:23.0 occ:1.00 OE2 A:GLU47 2.1 19.0 1.0 O A:HOH226 2.1 14.9 1.0 SG A:CYS44 2.3 20.1 1.0 O A:HOH217 2.7 20.6 1.0 CD A:GLU47 3.1 17.5 1.0 CB A:CYS44 3.2 16.9 1.0 ZN A:ZN4 3.3 26.9 1.0 CG A:GLU47 3.4 15.6 1.0 OE1 A:GLU47 4.2 19.9 1.0 CB A:GLU47 4.5 13.6 1.0 CB A:GLU46 4.6 15.2 1.0 O A:HOH240 4.6 23.3 1.0 CA A:CYS44 4.6 17.0 1.0 N A:GLU47 4.7 13.0 1.0 C A:GLU46 4.9 13.7 1.0

Zinc binding site 2 out of 5 in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:21.3 occ:1.00 O A:HOH237 1.8 21.2 1.0 OE1 A:GLU113 2.0 14.4 1.0 OE2 A:GLU160 2.5 14.0 1.0 CD A:GLU113 2.7 16.8 1.0 OE2 A:GLU113 2.7 18.3 1.0 CD A:GLU160 3.3 12.1 1.0 OE1 A:GLU160 3.5 11.4 1.0 O A:HOH238 3.9 23.1 1.0 CE2 A:PHE158 4.1 9.1 1.0 CG A:GLU113 4.1 19.0 1.0 NZ A:LYS103 4.2 18.1 1.0 CD2 A:PHE158 4.5 8.8 1.0 CG A:GLU160 4.6 10.7 1.0 O A:HOH169 4.6 16.2 1.0 CE A:LYS103 4.6 16.6 1.0

Zinc binding site 3 out of 5 in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn3 b:28.4 occ:1.00 OE1 A:GLU97 2.1 26.6 1.0 O A:HOH12 2.3 11.7 1.0 CD A:GLU97 3.1 26.4 1.0 CB A:GLU97 3.3 24.5 1.0 CG A:GLU97 3.4 25.1 1.0 O A:HOH241 3.5 32.5 1.0 NH1 A:ARG124 4.1 21.3 1.0 OE2 A:GLU97 4.2 27.1 1.0 O A:GLU97 4.4 23.3 1.0 C A:GLU97 4.4 22.8 1.0 NE A:ARG99 4.5 18.2 0.5 CA A:GLU97 4.5 23.8 1.0 NH2 A:ARG124 4.6 19.8 1.0 CZ A:ARG124 4.8 18.9 1.0 NH2 A:ARG99 4.8 21.2 0.5

Zinc binding site 4 out of 5 in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn4 b:26.9 occ:1.00 SG A:CYS44 2.3 20.1 1.0 O A:HOH240 2.4 23.3 1.0 O A:HOH218 2.6 32.4 1.0 O A:HOH8 2.8 14.8 1.0 CB A:CYS44 3.3 16.9 1.0 ZN A:ZN1 3.3 23.0 1.0 O A:HOH217 3.7 20.6 1.0 ZN A:ZN5 3.8 44.5 1.0 CA A:CYS44 3.8 17.0 1.0 O A:HOH224 4.0 29.9 1.0 OE2 A:GLU46 4.1 21.3 1.0 C A:CYS44 4.7 16.0 1.0 N A:ARG45 4.8 15.5 1.0 OE2 A:GLU47 4.9 19.0 1.0 O A:HOH226 4.9 14.9 1.0 N A:CYS44 5.0 16.9 1.0

Zinc binding site 5 out of 5 in the Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structures of Spop-Substrate Complexes: Insights Into Architectures of Btb-CUL3 Ubiquitin Ligases: Spopmath- MACROH2ASBCPEP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn5 b:44.5 occ:1.00 OE2 A:GLU46 2.3 21.3 1.0 O A:HOH218 2.3 32.4 1.0 O A:HOH225 2.4 29.8 1.0 CD A:GLU46 2.9 20.9 1.0 OE1 A:GLU46 3.1 21.8 1.0 O A:HOH224 3.2 29.9 1.0 ZN A:ZN4 3.8 26.9 1.0 CG A:GLU46 4.2 17.5 1.0 NH2 A:ARG45 4.4 16.4 0.5 O A:HOH8 4.4 14.8 1.0 O A:HOH217 4.6 20.6 1.0 SG A:CYS44 4.6 20.1 1.0 NE A:ARG45 4.7 16.1 0.5 CB A:GLU46 4.9 15.2 1.0 CZ A:ARG45 4.9 18.2 0.5 N A:GLU46 5.0 14.9 1.0

M.Zhuang, M.F.Calabrese, J.Liu, M.B.Waddell, A.Nourse, M.Hammel, D.J.Miller, H.Walden, D.M.Duda, S.Steven, T.Hoggard, J.W.Harper, K.P.White, B.A.Schulman. Structure 9 To Be Published.