Atomistry » Zinc » PDB 3iew-3iq6 » 3io8
Atomistry »
  Zinc »
    PDB 3iew-3iq6 »
      3io8 »

Zinc in PDB 3io8: BIML12F in Complex with Bcl-Xl

Protein crystallography data

The structure of BIML12F in Complex with Bcl-Xl, PDB code: 3io8 was solved by P.M.Colman, E.F.Lee, W.D.Fairlie, B.J.Smith, P.E.Czabotar, H.Yang, B.E.Sleebs, G.Lessene, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.30 / 2.30
Space group P 62
Cell size a, b, c (Å), α, β, γ (°) 65.717, 65.717, 170.094, 90.00, 90.00, 120.00
R / Rfree (%) 18.5 / 23.1

Zinc Binding Sites:

The binding sites of Zinc atom in the BIML12F in Complex with Bcl-Xl (pdb code 3io8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the BIML12F in Complex with Bcl-Xl, PDB code: 3io8:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in 3io8

Go back to Zinc Binding Sites List in 3io8
Zinc binding site 1 out of 3 in the BIML12F in Complex with Bcl-Xl


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of BIML12F in Complex with Bcl-Xl within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn210

b:52.9
occ:1.00
O A:HOH211 2.7 35.5 1.0
O A:HOH217 3.2 49.9 1.0
N A:PRO-3 3.8 37.9 1.0
CA A:PRO-3 4.7 36.5 1.0
CD A:PRO-3 4.8 36.4 1.0
O A:PRO-3 4.9 38.2 1.0
C A:PRO-3 4.9 39.5 1.0
CD2 A:LEU-2 4.9 41.4 1.0

Zinc binding site 2 out of 3 in 3io8

Go back to Zinc Binding Sites List in 3io8
Zinc binding site 2 out of 3 in the BIML12F in Complex with Bcl-Xl


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of BIML12F in Complex with Bcl-Xl within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn210

b:58.3
occ:1.00
ND1 C:HIS113 2.3 56.7 1.0
O C:HOH215 2.6 44.4 1.0
CE1 C:HIS113 3.3 59.2 1.0
CG C:HIS113 3.3 61.8 1.0
CB C:HIS113 3.6 61.5 1.0
CA C:HIS113 4.3 63.6 1.0
NE2 C:HIS113 4.4 63.8 1.0
CD2 C:HIS113 4.5 63.7 1.0

Zinc binding site 3 out of 3 in 3io8

Go back to Zinc Binding Sites List in 3io8
Zinc binding site 3 out of 3 in the BIML12F in Complex with Bcl-Xl


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of BIML12F in Complex with Bcl-Xl within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn211

b:84.8
occ:1.00
N C:GLY-4 2.6 56.3 1.0
CA C:GLY-4 2.7 50.3 1.0
O C:GLY-4 3.3 48.1 1.0
C C:GLY-4 3.4 47.2 1.0
N C:PRO-3 4.6 47.7 1.0

Reference:

E.F.Lee, P.E.Czabotar, H.Yang, B.E.Sleebs, G.Lessene, P.M.Colman, B.J.Smith, W.D.Fairlie. Conformational Changes in Bcl-2 Pro-Survival Proteins Determine Their Capacity to Bind Ligands. J.Biol.Chem. V. 284 30508 2009.
ISSN: ISSN 0021-9258
PubMed: 19726685
DOI: 10.1074/JBC.M109.040725
Page generated: Wed Dec 16 04:26:41 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy