Zinc in PDB 3ht2: Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus

The structure of Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus, PDB code: 3ht2 was solved by L.Silvennoinen, T.Sandalova, G.Schneider, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.62 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	34.433, 97.255, 47.743, 90.00, 91.99, 90.00
R / Rfree (%)	19.3 / 24.4

The binding sites of Zinc atom in the Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus (pdb code 3ht2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus, PDB code: 3ht2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn150 b:16.5 occ:1.00 NE2 A:HIS95 2.1 17.7 1.0 NE2 A:HIS55 2.1 16.5 1.0 NE2 A:HIS59 2.2 19.4 1.0 NE2 A:HIS53 2.2 17.8 1.0 O A:HOH185 2.3 21.3 1.0 O A:HOH146 2.5 17.1 1.0 CE1 A:HIS95 3.0 19.7 1.0 CE1 A:HIS55 3.1 18.2 1.0 CD2 A:HIS53 3.1 17.2 1.0 CD2 A:HIS55 3.1 16.0 1.0 CD2 A:HIS95 3.1 18.8 1.0 CD2 A:HIS59 3.2 20.8 1.0 CE1 A:HIS59 3.2 20.9 1.0 CE1 A:HIS53 3.3 17.7 1.0 O A:HOH172 3.9 24.2 1.0 ND1 A:HIS95 4.1 18.5 1.0 ND1 A:HIS55 4.2 17.9 1.0 CG A:HIS95 4.2 18.9 1.0 CG A:HIS55 4.3 17.5 1.0 CG A:HIS53 4.3 17.4 1.0 ND1 A:HIS59 4.3 20.8 1.0 CG A:HIS59 4.3 19.1 1.0 ND1 A:HIS53 4.3 16.0 1.0 O A:HOH281 4.6 39.5 1.0 O A:HOH192 4.9 27.0 1.0 CH2 A:TRP57 4.9 21.0 1.0

Zinc binding site 2 out of 2 in the Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Zink Containing Polyketide Cyclase Remf From Streptomyces Resistomycificus within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn150 b:17.6 occ:1.00 NE2 C:HIS59 2.1 19.8 1.0 NE2 C:HIS95 2.1 17.0 1.0 NE2 C:HIS55 2.1 15.1 1.0 O C:HOH184 2.2 19.7 1.0 NE2 C:HIS53 2.2 18.7 1.0 O C:HOH147 2.3 15.3 1.0 CE1 C:HIS95 3.0 18.9 1.0 CE1 C:HIS59 3.1 20.1 1.0 CE1 C:HIS55 3.1 18.8 1.0 CD2 C:HIS53 3.1 17.5 1.0 CD2 C:HIS59 3.2 20.8 1.0 CD2 C:HIS95 3.2 17.6 1.0 CD2 C:HIS55 3.2 15.4 1.0 CE1 C:HIS53 3.3 17.5 1.0 O C:HOH195 3.8 28.4 1.0 ND1 C:HIS95 4.2 17.3 1.0 ND1 C:HIS59 4.2 20.1 1.0 ND1 C:HIS55 4.2 17.2 1.0 CG C:HIS95 4.3 18.1 1.0 CG C:HIS59 4.3 19.8 1.0 CG C:HIS53 4.3 18.1 1.0 CG C:HIS55 4.3 17.7 1.0 ND1 C:HIS53 4.3 17.5 1.0 O C:HOH189 4.5 27.1 1.0 O C:HOH248 4.5 46.8 1.0 CH2 C:TRP57 4.8 22.7 1.0

L.Silvennoinen, T.Sandalova, G.Schneider. The Polyketide Cyclase Remf From Streptomyces Resistomycificus Contains An Unusual Octahedral Zinc Binding Site Febs Lett. V. 583 2917 2009.
ISSN: ISSN 0014-5793
PubMed: 19665022
DOI: 10.1016/J.FEBSLET.2009.07.061