Zinc in PDB 3fca: Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe

All present enzymatic activity of Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe:
2.5.1.47;

The structure of Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe, PDB code: 3fca was solved by F.Wang, H.Lee, G.Spraggon, P.G.Schultz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	96.23 / 2.15
Space group	P 42 21 2
Cell size a, b, c (Å), α, β, γ (°)	135.858, 135.858, 74.939, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 24.4

The binding sites of Zinc atom in the Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe (pdb code 3fca). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe, PDB code: 3fca:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:53.7 occ:1.00 N06 A:HQA22 2.1 30.4 1.0 O09 A:HQA22 2.3 28.9 1.0 O A:HOH584 2.7 24.2 1.0 O A:HOH606 2.9 49.0 1.0 C07 A:HQA22 3.0 29.9 1.0 C08 A:HQA22 3.0 29.6 1.0 C05 A:HQA22 3.1 29.4 1.0 O A:HOH616 3.2 38.6 1.0 C13 A:HQA22 4.3 29.6 1.0 CB A:ARG13 4.3 30.0 1.0 C04 A:HQA22 4.4 28.6 1.0 C10 A:HQA22 4.4 29.6 1.0 CG A:ARG13 4.5 32.1 1.0 NE A:ARG13 4.7 41.2 1.0 C14 A:HQA22 4.9 28.1 1.0

Zinc binding site 2 out of 2 in the Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As Biophysical Probe within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn500 b:52.3 occ:1.00 N06 B:HQA22 2.2 30.1 1.0 O09 B:HQA22 2.2 31.1 1.0 O B:HOH602 2.6 21.7 1.0 O B:HOH541 3.0 35.6 1.0 C07 B:HQA22 3.0 29.6 1.0 C08 B:HQA22 3.1 30.3 1.0 C05 B:HQA22 3.2 30.0 1.0 O B:HOH663 3.2 43.2 1.0 C13 B:HQA22 4.4 29.7 1.0 C10 B:HQA22 4.4 30.3 1.0 CB B:ARG13 4.5 29.8 1.0 C04 B:HQA22 4.5 29.0 1.0 NE B:ARG13 4.7 39.5 1.0 CG B:ARG13 4.9 32.7 1.0 C14 B:HQA22 5.0 29.8 1.0

H.S.Lee, G.Spraggon, P.G.Schultz, F.Wang. Genetic Incorporation of A Metal-Ion Chelating Amino Acid Into Proteins As A Biophysical Probe. J.Am.Chem.Soc. V. 131 2481 2009.
ISSN: ISSN 0002-7863
PubMed: 19193005
DOI: 10.1021/JA808340B