Zinc in PDB 3eqt: Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna

The structure of Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna, PDB code: 3eqt was solved by P.Li, X.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	116.458, 54.191, 67.203, 90.00, 97.26, 90.00
R / Rfree (%)	21.3 / 25.4

The binding sites of Zinc atom in the Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna (pdb code 3eqt). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna, PDB code: 3eqt:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:32.0 occ:1.00 SG A:CYS559 2.3 28.5 1.0 SG A:CYS612 2.4 26.3 1.0 SG A:CYS615 2.4 30.3 1.0 SG A:CYS556 2.4 25.3 1.0 CB A:CYS612 3.1 25.1 1.0 CB A:CYS556 3.1 22.8 1.0 CB A:CYS559 3.3 28.2 1.0 CB A:CYS615 3.4 36.2 1.0 N A:CYS559 3.7 27.5 1.0 N A:CYS615 3.8 33.4 1.0 CA A:CYS559 4.1 28.9 1.0 CA A:CYS615 4.1 32.7 1.0 CB A:GLU617 4.4 32.6 1.0 CB A:ASN614 4.5 26.2 1.0 CB A:ASN558 4.6 28.8 1.0 CA A:CYS612 4.6 23.0 1.0 CA A:CYS556 4.6 24.6 1.0 C A:ASN558 4.8 31.1 1.0 C A:ASN614 4.8 36.4 1.0 C A:CYS615 4.8 31.0 1.0 CZ2 A:TRP619 4.9 24.1 1.0 NE1 A:TRP619 4.9 22.9 1.0 CG2 A:VAL561 4.9 30.5 1.0 C A:CYS559 4.9 26.1 1.0 N A:GLU617 4.9 32.1 1.0 OD1 A:ASN614 4.9 29.6 1.0 ND2 A:ASN558 4.9 33.5 1.0 N A:GLY616 4.9 28.4 1.0 N A:MET560 5.0 24.9 1.0 N A:ASN558 5.0 26.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human LGP2 C-Terminal Domain in Complex with Dsrna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:72.5 occ:1.00 SG B:CYS612 2.4 59.5 1.0 SG B:CYS556 2.5 65.3 1.0 SG B:CYS559 2.6 80.4 1.0 SG B:CYS615 2.6 81.3 1.0 CB B:CYS556 3.0 57.9 1.0 CB B:CYS612 3.2 59.7 1.0 CB B:CYS559 3.2 76.1 1.0 CB B:CYS615 3.4 78.0 1.0 N B:CYS559 3.4 74.6 1.0 N B:CYS615 3.9 77.5 1.0 CA B:CYS559 3.9 75.7 1.0 CB B:ASN558 4.2 73.7 1.0 CA B:CYS615 4.2 75.8 1.0 OD1 B:ASN614 4.4 79.8 1.0 CA B:CYS556 4.5 56.9 1.0 CB B:ASN614 4.5 78.2 1.0 C B:ASN558 4.5 73.5 1.0 CG1 B:VAL561 4.6 73.0 1.0 N B:MET560 4.6 75.0 1.0 C B:CYS559 4.7 75.7 1.0 CA B:CYS612 4.7 64.3 1.0 CB B:GLU617 4.7 70.0 1.0 CA B:ASN558 4.8 72.1 1.0 C B:ASN614 4.8 79.0 1.0 OD1 B:ASN558 4.8 74.3 1.0 N B:ASN558 4.9 69.2 1.0 CG B:ASN614 4.9 79.7 1.0 CZ2 B:TRP619 4.9 47.5 1.0 C B:CYS556 4.9 59.5 1.0 C B:CYS615 4.9 73.5 1.0 N B:GLY616 5.0 74.5 1.0 O B:CYS556 5.0 62.8 1.0

X.Li, C.T.Ranjith-Kumar, M.T.Brooks, S.Dharmaiah, A.B.Herr, C.Kao, P.Li. The Rig-I-Like Receptor LGP2 Recognizes the Termini of Double-Stranded Rna J.Biol.Chem. V. 284 13881 2009.
ISSN: ISSN 0021-9258
PubMed: 19278996
DOI: 10.1074/JBC.M900818200