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Atomistry » Zinc » PDB 3eju-3eyd » 3epz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3eju-3eyd » 3epz » |
Zinc in PDB 3epz: Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1Enzymatic activity of Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1
All present enzymatic activity of Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1:
2.1.1.37; Protein crystallography data
The structure of Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1, PDB code: 3epz
was solved by
J.R.Walker,
G.V.Avvakumov,
S.Xue,
Y.Li,
C.Bountra,
J.Weigelt,
C.H.Arrowsmith,
A.M.Edwards,
A.Bochkarev,
S.Dhe-Paganon,
Structuralgenomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3epz:
The structure of Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1
(pdb code 3epz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1, PDB code: 3epz: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3epzGo back to Zinc Binding Sites List in 3epz
Zinc binding site 1 out
of 2 in the Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3epzGo back to Zinc Binding Sites List in 3epz
Zinc binding site 2 out
of 2 in the Structure of the Replication Foci-Targeting Sequence of Human Dna Cytosine Methyltransferase DNMT1
Mono view Stereo pair view
Reference:
F.Syeda,
R.L.Fagan,
M.Wean,
G.V.Avvakumov,
J.R.Walker,
S.Xue,
S.Dhe-Paganon,
C.Brenner.
The Replication Focus Targeting Sequence (Rfts) Domain Is A Dna-Competitive Inhibitor of DNMT1. J.Biol.Chem. V. 286 15344 2011.
Page generated: Wed Dec 16 04:16:44 2020
ISSN: ISSN 0021-9258 PubMed: 21389349 DOI: 10.1074/JBC.M110.209882 |
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