Zinc in PDB 3eh2: Crystal Structure of the Human Copii-Coat Protein SEC24C

The structure of Crystal Structure of the Human Copii-Coat Protein SEC24C, PDB code: 3eh2 was solved by J.Goldberg, J.D.Mancias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.78 / 2.35
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	69.690, 182.980, 201.830, 90.00, 90.00, 90.00
R / Rfree (%)	24.1 / 28.4

The binding sites of Zinc atom in the Crystal Structure of the Human Copii-Coat Protein SEC24C (pdb code 3eh2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the Human Copii-Coat Protein SEC24C, PDB code: 3eh2:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of the Human Copii-Coat Protein SEC24C


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Human Copii-Coat Protein SEC24C within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn800 b:27.8 occ:1.00 SG A:CYS98 2.3 22.3 1.0 SG A:CYS101 2.4 22.0 1.0 SG A:CYS120 2.4 21.1 1.0 SG A:CYS123 2.4 28.2 1.0 CB A:CYS98 3.1 21.4 1.0 CB A:CYS120 3.1 25.2 1.0 CB A:CYS101 3.3 21.3 1.0 CB A:CYS123 3.4 20.6 1.0 N A:CYS101 3.7 25.6 1.0 N A:CYS123 3.7 28.0 1.0 CA A:CYS101 4.0 25.3 1.0 CA A:CYS123 4.1 23.7 1.0 CB A:CYS125 4.4 18.8 1.0 CA A:CYS98 4.5 20.6 1.0 CA A:CYS120 4.6 20.0 1.0 CB A:PHE122 4.6 23.6 1.0 N A:CYS125 4.6 27.9 1.0 C A:CYS123 4.6 24.8 1.0 N A:SER124 4.7 22.0 1.0 C A:PHE122 4.7 23.2 1.0 C A:CYS101 4.7 24.2 1.0 CB A:ARG100 4.7 32.7 1.0 N A:LYS102 4.8 23.9 1.0 C A:ARG100 4.8 29.7 1.0 CB A:ALA103 4.9 26.3 1.0 N A:ALA103 5.0 24.3 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of the Human Copii-Coat Protein SEC24C


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Human Copii-Coat Protein SEC24C within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn800 b:40.4 occ:1.00 SG B:CYS120 2.3 41.0 1.0 SG B:CYS101 2.4 40.7 1.0 SG B:CYS98 2.4 41.4 1.0 SG B:CYS123 2.5 40.5 1.0 CB B:CYS98 3.1 47.0 1.0 CB B:CYS120 3.1 44.8 1.0 CB B:CYS101 3.3 41.8 1.0 CB B:CYS123 3.4 43.0 1.0 N B:CYS101 3.6 50.0 1.0 N B:CYS123 3.8 43.1 1.0 CA B:CYS101 4.0 44.1 1.0 CA B:CYS123 4.2 44.8 1.0 CA B:CYS98 4.5 46.1 1.0 CB B:PHE122 4.5 45.7 1.0 CB B:CYS125 4.5 57.8 1.0 CA B:CYS120 4.6 46.4 1.0 N B:LYS102 4.7 38.0 1.0 C B:CYS101 4.7 40.7 1.0 C B:ARG100 4.7 52.7 1.0 CB B:ARG100 4.7 58.9 1.0 CB B:ALA103 4.8 39.1 1.0 C B:PHE122 4.8 45.3 1.0 C B:CYS123 4.8 48.9 1.0 N B:ARG100 4.8 52.2 1.0 N B:ALA103 4.9 34.6 1.0 N B:CYS125 4.9 58.6 1.0 CA B:ARG100 5.0 52.5 1.0 C B:CYS98 5.0 52.0 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of the Human Copii-Coat Protein SEC24C


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Human Copii-Coat Protein SEC24C within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn800 b:26.7 occ:1.00 SG C:CYS101 2.4 24.1 1.0 SG C:CYS120 2.4 28.5 1.0 SG C:CYS123 2.4 27.0 1.0 SG C:CYS98 2.4 29.1 1.0 CB C:CYS120 3.1 30.5 1.0 CB C:CYS98 3.2 28.6 1.0 CB C:CYS101 3.2 20.1 1.0 CB C:CYS123 3.5 30.2 1.0 N C:CYS101 3.7 19.6 1.0 N C:CYS123 3.8 33.1 1.0 CA C:CYS101 4.0 23.5 1.0 CA C:CYS123 4.1 29.4 1.0 CB C:CYS125 4.5 22.9 1.0 CB C:PHE122 4.5 33.3 1.0 CA C:CYS120 4.6 32.9 1.0 C C:CYS101 4.6 19.1 1.0 CA C:CYS98 4.6 32.8 1.0 N C:LYS102 4.7 23.6 1.0 CB C:ALA103 4.7 19.7 1.0 C C:PHE122 4.7 35.1 1.0 C C:CYS123 4.7 34.5 1.0 N C:CYS125 4.8 25.4 1.0 N C:ALA103 4.8 21.9 1.0 C C:ARG100 4.9 26.7 1.0 N C:PHE122 5.0 35.6 1.0 N C:SER124 5.0 28.6 1.0 CA C:PHE122 5.0 29.1 1.0

J.D.Mancias, J.Goldberg. Structural Basis of Cargo Membrane Protein Discrimination By the Human Copii Coat Machinery. Embo J. V. 27 2918 2008.
ISSN: ISSN 0261-4189
PubMed: 18843296
DOI: 10.1038/EMBOJ.2008.208