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Atomistry » Zinc » PDB 3e2d-3eb5 » 3e34 » |
Zinc in PDB 3e34: Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10Enzymatic activity of Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10
All present enzymatic activity of Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10:
2.5.1.58; 2.5.1.59; Protein crystallography data
The structure of Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10, PDB code: 3e34
was solved by
M.A.Hast,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10
(pdb code 3e34). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10, PDB code: 3e34: Zinc binding site 1 out of 1 in 3e34Go back to Zinc Binding Sites List in 3e34
Zinc binding site 1 out
of 1 in the Protein Farnesyltransferase Complexed with Fpp and Ethylenediamine-Scaffold Inhibitor 10
Mono view Stereo pair view
Reference:
M.A.Hast,
S.Fletcher,
C.G.Cummings,
E.E.Pusateri,
M.A.Blaskovich,
K.Rivas,
M.H.Gelb,
W.C.Van Voorhis,
S.M.Sebti,
A.D.Hamilton,
L.S.Beese.
Structural Basis For Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase. Chem.Biol. V. 16 181 2009.
Page generated: Wed Dec 16 04:14:50 2020
ISSN: ISSN 1074-5521 PubMed: 19246009 DOI: 10.1016/J.CHEMBIOL.2009.01.014 |
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